GTF2E1 and GTF2A1

Number of citations of the paper that reports this interaction (PMID 11509574)
7

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		GTF2E1	GTF2A1
Gene Name		general transcription factor IIE, polypeptide 1, alpha 56kDa	general transcription factor IIA, 1, 19/37kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Intermediate Filament Cytoskeleton	Nucleoplasm Transcription Factor TFIIA Complex Cytoplasm
	Molecular Function	Protein Binding Sequence-specific DNA Binding Metal Ion Binding	DNA Binding Transcription Coactivator Activity Protein Binding Transcription Factor Binding TBP-class Protein Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		28 interactors: AES APP CBFA2T2 CDK7 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F2 GTF2H1 GTF2H4 IKBKG MDM2 PCBD2 POLR2A SND1 SRPK2 TAF1 TAF11 TAF6 TBP TCEA1 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1	18 interactors: BCL3 CREB1 CSNK2A1 CSNK2A2 GTF2A2 GTF2E1 GTF2E2 GTF2F1 HMGB1 NCOA6 NFYA TAF1 TAF4 TAF4B TASP1 TBP TBPL1 TRIP4
Entrez ID		2960	2957
HPRD ID		01799	02748
Ensembl ID		ENSG00000153767	ENSG00000165417
Uniprot IDs		P29083	P52655
PDB IDs		1VD4 2JTX 2RNQ 2RNR	1NVP
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription Initiation From RNA Polymerase II Promoter Viral Process DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Positive Regulation Of Viral Process Positive Regulation Of Viral Transcription Regulation Of Viral Process Positive Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Viral Transcription Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process 7-methylguanosine MRNA Capping Positive Regulation Of Cellular Biosynthetic Process 7-methylguanosine RNA Capping Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase I Promoter Nucleotide-excision Repair Positive Regulation Of Metabolic Process Regulation Of Cellular Process Nucleotide-excision Repair, DNA Damage Removal Positive Regulation Of Transcription, DNA-templated MRNA Processing DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter	Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Elongation Transcription Initiation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of Cellular Process Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Metabolic Process Rhythmic Process Intracellular Estrogen Receptor Signaling Pathway Regulation Of DNA-templated Transcription, Initiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Secretory Granule Organization Regulation Of Proteasomal Protein Catabolic Process Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Apoptotic Cell Clearance
Tagcloud ?		avenues bioinformatics bl canonical conferring dhx8 disrupted dnaja1 galactosidase hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Difference) ?		avenues bioinformatics bl canonical conferring dhx8 disrupted dnaja1 galactosidase hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Intersection) ?