GTF2E1 and SND1

Number of citations of the paper that reports this interaction (PubMedID 7651391)
62

Data Source:
HPRD (in vitro, in vivo)

		GTF2E1	SND1
Description		general transcription factor IIE subunit 1	staphylococcal nuclease and tudor domain containing 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol	Nucleus Cytoplasm Cytosol Membrane RNAi Effector Complex Melanosome Extracellular Exosome Dense Body
	Molecular Function	Protein Binding Zinc Ion Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding	Nucleic Acid Binding Transcription Coregulator Activity RNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity Cadherin Binding RISC Complex Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter	Osteoblast Differentiation MRNA Catabolic Process Regulation Of Cell Cycle Process MiRNA Catabolic Process Regulatory NcRNA-mediated Gene Silencing
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Cadmium levels ( 26025379) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Fruit consumption ( 32066663) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Haemorrhoidal disease ( 33888516) Hemoglobin A1c levels ( 29403010) Number of sexual partners ( 30643258) Offspring birth weight ( 31043758) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 23532257 32499647)
Interacting Genes		34 interacting genes: APP CBFA2T2 CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 IKBKG NRARP OGT PCBD2 SND1 SRPK2 TAF1 TAF11 TAF6 TBC1D21 TBP TCEA1 TLE5 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1	28 interacting genes: APP CEBPA CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 HOXA1 LINC00624 LZTR1 MAK MYB MYBL2 PDE4B PIM1 POLR2A PRPF8 PTGER4 RBPJ RNF10 RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 SUMO2 UBE2I
Entrez ID		2960	27044
HPRD ID		01799	03714
Ensembl ID		ENSG00000153767	ENSG00000197157
Uniprot IDs		P29083	A0A140VK49 Q7KZF4
PDB IDs		1VD4 2JTX 2RNQ 2RNR 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L 7EG9 7EGA 7EGB 7EGC 7ENA 7ENC 7LBM 7NVR 7NVS 7NVT 7NVU 7NVV 7NVW 7NVX 7NVY 7NVZ 7NW0 8BVW 8BYQ 8GXQ 8GXS 8S51 8S52 8S54 8S55 8S5N 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMG 5M9O 7KNW 7KNX
Enriched GO Terms of Interacting Partners?		Transcription Factor TFIID Complex Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Initiation Transcription By RNA Polymerase II RNA Polymerase II General Transcription Initiation Factor Activity DNA-templated Transcription Transcription Factor TFIIH Core Complex Transcription Factor TFIIH Holo Complex Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II General Transcription Initiation Factor Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Preinitiation Complex Assembly Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Elongation Nucleotide-excision Repair Transcription Preinitiation Complex Assembly Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II TBP-class Protein Binding Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Protein-DNA Complex Assembly Nucleus Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Core TFIIH Complex Portion Of Holo TFIIH Complex Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Preinitiation Complex Nucleoplasm Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Initiation Transcription Elongation By RNA Polymerase II Regulation Of Metabolic Process Transcription Factor TFIIA Complex RNA Polymerase II Core Promoter Sequence-specific DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process	Formation Of Quadruple SL/U4/U5/U6 SnRNP Spliceosomal Tri-snRNP Complex Assembly Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process U4/U6 X U5 Tri-snRNP Complex Spliceosomal SnRNP Assembly Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Factor TFIIE Complex Positive Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Cellular Component Assembly Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Transcription Coactivator Binding Nucleoplasm Negative Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Cell Activation Involved In Immune Response U6 SnRNA Binding Response To Cytokine Response To Peptide Protein-containing Complex Organization DNA Binding Regulation Of MiRNA Transcription Mammary Gland Epithelial Cell Proliferation Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Protein Catabolic Process Regulation Of Stem Cell Proliferation Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of MiRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Transcription Factor Binding SUMO Transferase Activity U5 SnRNP Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Cellular Response To Cytokine Stimulus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?