STATH and KCNJ6

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		STATH	KCNJ6
Name		statherin	potassium inwardly rectifying channel subfamily J member 6
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex
	Molecular Function	Protein Binding Extracellular Matrix Constituent, Lubricant Activity Structural Constituent Of Tooth Enamel Hydroxyapatite Binding	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity
	Biological Process	Ossification Regulation Of Bone Mineralization Negative Regulation Of Bone Mineralization Biomineral Tissue Development Defense Response To Bacterium Saliva Secretion	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		None	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		None	Ethanol Halothane Ifenprodil Isavuconazole
GWAS		No GWAS studies recorded	Body size at age 10 ( 32376654 ) Clostridioides difficle infection ( 33841421 ) Electroencephalographic traits in alcoholism ( 22554406 ) Response to placebo treatment in childhood asthma (FVC change) ( 31557306 ) Rosacea symptom severity ( 29771307 )
Interacting Genes		30 interacting genes: AQP6 C16orf92 DERL3 ERGIC3 FAM209A FAM210B FCRL3 FKBP7 GET3 GPR152 GPR42 KCNJ6 LEUTX MRM1 MTIF3 OPRPN OVGP1 REEP4 SAR1A SGPL1 SLC10A1 SLC10A6 SLC35H1 SLC39A2 SLC61A1 SPNS3 TFAM TLCD4 TMEM80 TMX2	70 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMAS CMTM5 CNPY3 COL4A5 CXXC5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 GIPC1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MAP1S MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PICK1 PLLP PMP22 PNLIPRP1 PTPRD RPRM RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZBTB38 ZDHHC24
Entrez ID		6779	3763
HPRD ID		01696	02929
Ensembl ID		ENSG00000126549	ENSG00000157542
Uniprot IDs		P02808	P48051
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Bile Acid:sodium Symporter Activity	Membrane Presynaptic Membrane Trans-synaptic Signaling Synaptic Signaling Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Chemical Synaptic Transmission Negative Regulation Of Dopamine Secretion G-protein Activated Inward Rectifier Potassium Channel Activity Compact Myelin Inward Rectifier Potassium Channel Complex Regulation Of Sodium Ion Transport Protein Targeting Regulation Of Presynaptic Membrane Potential Regulation Of Monoatomic Ion Transport Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Golgi Trans Cisterna Negative Regulation Of Synaptic Transmission