KCNJ6 and MAP1S

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		KCNJ6	MAP1S
Description		potassium inwardly rectifying channel subfamily J member 6	microtubule associated protein 1S
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Microtubule Organizing Center Spindle Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Microtubule Cytoskeleton Dendrite Cell Projection Neuronal Cell Body Synapse Perinuclear Region Of Cytoplasm Mitotic Spindle Microtubule
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding G-protein Activated Inward Rectifier Potassium Channel Activity	DNA Binding Actin Binding DNA Nuclease Activity Protein Binding Microtubule Binding Tubulin Binding Identical Protein Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Autophagy Apoptotic Process Mitotic Spindle Organization Nervous System Development Axonogenesis Brain Development Dendrite Development Regulation Of Microtubule Depolymerization Microtubule Anchoring At Centrosome Mitochondrion Transport Along Microtubule Neuron Projection Morphogenesis Metaphase Chromosome Alignment
Pathways		Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Ethanol Halothane Ifenprodil Isavuconazole
Diseases
GWAS		Body size at age 10 ( 32376654) Clostridioides difficle infection ( 33841421) Electroencephalographic traits in alcoholism ( 22554406) Response to placebo treatment in childhood asthma (FVC change) ( 31557306) Rosacea symptom severity ( 29771307)	Coronary artery disease ( 29212778 33020668) Height ( 28552196)
Interacting Genes		70 interacting genes: ADRB2 AIG1 APOD BCL2L2 BET1 BIRC5 C14orf180 CMAS CMTM5 CNPY3 COL4A5 CXXC5 DLG1 DRD2 EDDM3B ERG28 FAM20B FIS1 FUNDC2 FXYD6 GABBR1 GIPC1 HMOX2 ICMT ITGAM KCNJ3 KCNJ9 LEPROTL1 LPAR3 LPCAT2 MAP1S MIP MYO15B NINJ2 ORMDL2 PEX11G PEX16 PICK1 PLLP PMP22 PNLIPRP1 PTPRD RPRM RTP2 SCAMP4 SCARF1 SCD SERTM1 STATH STRIT1 SYT3 THSD7B TM6SF2 TMEM107 TMEM120B TMEM203 TMEM208 TMEM218 TMPPE TNFRSF10C TSPO2 UBIAD1 UNC50 UPK1B VSTM1 XIAP YIPF1 YIPF6 ZBTB38 ZDHHC24	15 interacting genes: ATM BPY2 BPY2C FILNC1 HDAC4 KCNJ6 LRPPRC MAP1LC3A NLGN3 PIN1 RASSF1 SLC2A4 SOCS3 SRPK2 VHL
Entrez ID		3763	55201
HPRD ID		02929	10461
Ensembl ID		ENSG00000157542	ENSG00000130479
Uniprot IDs		P48051	Q66K74
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Presynaptic Membrane Trans-synaptic Signaling Synaptic Signaling Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Chemical Synaptic Transmission Negative Regulation Of Dopamine Secretion G-protein Activated Inward Rectifier Potassium Channel Activity Compact Myelin Inward Rectifier Potassium Channel Complex Regulation Of Sodium Ion Transport Protein Targeting Regulation Of Presynaptic Membrane Potential Regulation Of Monoatomic Ion Transport Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Golgi Trans Cisterna Negative Regulation Of Synaptic Transmission	HECT Domain Binding Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Protein Stabilization Response To Decreased Oxygen Levels Response To Oxygen Levels Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Protein Stability Cellular Response To Hypoxia Negative Regulation Of Catabolic Process Negative Regulation Of Receptor Signaling Pathway Via STAT Peptidyl-serine Phosphorylation Cis-trans Isomerase Activity Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane
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