SSTR4 and CORT

Number of citations of the paper that reports this interaction (PMID 9205124)
10

Data Source:
BioGRID (unspecified method)
HPRD (in vivo)

		SSTR4	CORT
Gene Name		somatostatin receptor 4	cortistatin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Extracellular Space
	Molecular Function	Somatostatin Receptor Activity Neuropeptide Binding	G-protein Coupled Receptor Binding Neuropeptide Hormone Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Synaptic Transmission Negative Regulation Of Cell Proliferation Cell Migration Arachidonic Acid Metabolic Process Negative Regulation Of CAMP Metabolic Process Forebrain Development Somatostatin Signaling Pathway Positive Regulation Of MAPK Cascade Cellular Response To Glucocorticoid Stimulus	Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Synaptic Transmission
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		2 interactors: CORT SST	7 interactors: GHSR MRGPRX2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
Entrez ID		6754	1325
HPRD ID		01676	04150
Ensembl ID		ENSG00000132671	ENSG00000241563
Uniprot IDs		P31391	O00230 Q8IUV6
PDB IDs
Enriched GO Terms of Interacting Partners?		Hormone-mediated Apoptotic Signaling Pathway Synaptic Transmission Cell-cell Signaling Hyperosmotic Response G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway	Somatostatin Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Estradiol Stimulus Neuropeptide Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Estrogen Stimulus G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Response To Peptide Hormone Cellular Response To Organonitrogen Compound Cellular Response To Steroid Hormone Stimulus Response To Peptide G-protein Coupled Receptor Signaling Pathway Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Cellular Response To Hormone Stimulus Response To Organonitrogen Compound Cell-cell Signaling Response To Estradiol Cellular Response To Organic Cyclic Compound Response To Hormone Cellular Response To Lipid Response To Glucocorticoid Response To Steroid Hormone Response To Corticosteroid Synaptic Transmission Response To Estrogen Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Response To Lipid Response To Organic Cyclic Compound Cellular Response To Organic Substance Response To Nutrient Levels Cerebellum Development Forebrain Development Response To Extracellular Stimulus Metencephalon Development Response To Organic Substance Hindbrain Development Response To Starvation Regulation Of Cell Proliferation Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Signal Transduction Brain Development Head Development Multicellular Organismal Reproductive Process Regulation Of Hormone Secretion Signaling Multicellular Organism Reproduction
Tagcloud ?		arrays breast cohort component correlated correlation distribution epidermal estrogen evaluate hypothalamic independent interested luminal marker markers materials micro population principal produced sample somatostatin sstr2 subtype subtypes tma tumors	b10 beta2 bioassays cleft clefts congenic corticosteroid dynamical dysmorphogenesis e14 fraser iir juriloff learn logic malformation outline palatal palate palates palatogenesis plasmin plasminogen proposes rules sequester slower tgf urokinase
Tagcloud (Difference) ?		arrays breast cohort component correlated correlation distribution epidermal estrogen evaluate hypothalamic independent interested luminal marker markers materials micro population principal produced sample somatostatin sstr2 subtype subtypes tma tumors	b10 beta2 bioassays cleft clefts congenic corticosteroid dynamical dysmorphogenesis e14 fraser iir juriloff learn logic malformation outline palatal palate palates palatogenesis plasmin plasminogen proposes rules sequester slower tgf urokinase
Tagcloud (Intersection) ?