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SSTR3 and CORT
Number of citations of the paper that reports this interaction (PubMedID
9125122
)
0
Data Source:
BioGRID
(unspecified method)
HPRD
(in vivo)
SSTR3
CORT
Description
somatostatin receptor 3
cortistatin
Image
GO Annotations
Cellular Component
Plasma Membrane
Cilium
Membrane
Neuron Projection
Ciliary Membrane
Non-motile Cilium
Extracellular Region
Extracellular Space
Synapse
Molecular Function
G Protein-coupled Receptor Activity
Somatostatin Receptor Activity
Signaling Receptor Binding
Protein Binding
Neuropeptide Binding
G Protein-coupled Receptor Binding
Hormone Activity
Neuropeptide Hormone Activity
Protein Binding
Receptor Ligand Activity
Biological Process
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Neuropeptide Signaling Pathway
Cell-cell Signaling
Negative Regulation Of Cell Population Proliferation
Hormone-mediated Apoptotic Signaling Pathway
Somatostatin Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Chemical Synaptic Transmission
Regulation Of Cell Migration
Pathways
Peptide ligand-binding receptors
G alpha (i) signalling events
BBSome-mediated cargo-targeting to cilium
Peptide ligand-binding receptors
G alpha (i) signalling events
Drugs
Pasireotide
Somatostatin
Lutetium Lu 177 dotatate
Edotreotide gallium Ga-68
Diseases
GWAS
Male-pattern baldness (
28196072
)
Interacting Genes
5 interacting genes:
CORT
GNAI1
LNX1
SST
TP53
7 interacting genes:
GHSR
MRGPRX2
SSTR1
SSTR2
SSTR3
SSTR4
SSTR5
Entrez ID
6753
1325
HPRD ID
01675
04150
Ensembl ID
ENSG00000278195
ENSG00000241563
Uniprot IDs
P32745
O00230
Q8IUV6
PDB IDs
8XIQ
8XIR
7S8L
7S8M
7VDL
7VV4
8X8L
Enriched GO Terms of Interacting Partners
?
Trans-synaptic Signaling
Chemical Synaptic Transmission
Regulation Of Telomere Maintenance Via Telomerase
Response To Xenobiotic Stimulus
Disordered Domain Specific Binding
Regulation Of Neuroblast Proliferation
Gastrulation
T Cell Differentiation In Thymus
Negative Regulation Of Gliogenesis
Regulation Of Telomere Maintenance Via Telomere Lengthening
Neuroblast Proliferation
Apoptotic Signaling Pathway
Synaptic Signaling
Signaling
Cell Communication
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Receptor Ligand Activity
Hormone Activity
Cell-cell Signaling
G Protein-coupled Receptor Binding
Mesenchymal Stem Cell Differentiation
Oviduct Development
Positive Regulation Of Determination Of Dorsal Identity
Negative Regulation Of Mitotic Cell Cycle, Embryonic
Regulation Of Gliogenesis
Stem Cell Differentiation
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Centrosome
Beta-catenin-ICAT Complex
Fungiform Papilla Formation
Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Positive Regulation Of Neuron Apoptotic Process
Beta-catenin-TCF7L2 Complex
Glial Cell Fate Determination
Negative Regulation Of Nervous System Development
Astrocyte-dopaminergic Neuron Signaling
Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Renal Inner Medulla Development
Scrib-APC-beta-catenin Complex
Regulation Of Centriole-centriole Cohesion
Renal Outer Medulla Development
Renal Vesicle Formation
Embryonic Skeletal Limb Joint Morphogenesis
Regulation Of Fibroblast Proliferation
Lung Induction
Regulation Of Telomere Maintenance
Neural Precursor Cell Proliferation
Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation
Positive Regulation Of Branching Involved In Lung Morphogenesis
Neural Plate Development
Somatostatin Receptor Activity
Somatostatin Signaling Pathway
Neuropeptide Binding
G Protein-coupled Receptor Activity
Hormone-mediated Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Neuropeptide Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Neuron Projection
Response To Glucocorticoid
Response To Corticosteroid
Cellular Response To Lipid
Response To Steroid Hormone
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Corticosteroid Stimulus
Negative Regulation Of Cell Population Proliferation
Response To Lipid
Cellular Response To Steroid Hormone Stimulus
Regulation Of Cell Population Proliferation
Cellular Response To Hormone Stimulus
Response To Estradiol
Response To Hormone
Signal Transduction
Plasma Membrane
Cellular Response To Estradiol Stimulus
Positive Regulation Of Cytokinesis
Growth Hormone Secretagogue Receptor Activity
Ghrelin Secretion
Mast Cell Secretagogue Receptor Activity
Regulation Of Cytokinesis
Positive Regulation Of Cell Division
Negative Regulation Of Locomotion Involved In Locomotory Behavior
Regulation Of Hindgut Contraction
Positive Regulation Of Small Intestinal Transit
Growth Hormone-releasing Hormone Receptor Activity
Positive Regulation Of Small Intestine Smooth Muscle Contraction
Positive Regulation Of Eating Behavior
Regulation Of Gastric Motility
Positive Regulation Of Response To Food
Positive Regulation Of Appetite
Membrane
Regulation Of Insulin Secretion
Positive Regulation Of Gastro-intestinal System Smooth Muscle Contraction
Hormone-mediated Apoptotic Signaling Pathway
Regulation Of Cell Division
Regulation Of Locomotion Involved In Locomotory Behavior
Negative Regulation Of Norepinephrine Secretion
Growth Hormone Secretion
Regulation Of Peptide Hormone Secretion
Negative Regulation Of Macrophage Apoptotic Process
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