SSTR3

Gene Name		somatostatin receptor 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Nonmotile Primary Cilium Neuron Projection Ciliary Membrane
	Molecular Function	Somatostatin Receptor Activity Protein Binding Neuropeptide Binding
	Biological Process	Organelle Organization G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Cell-cell Signaling Synaptic Transmission Spermatogenesis Negative Regulation Of Cell Proliferation Hormone-mediated Apoptotic Signaling Pathway Cerebellum Development Forebrain Development Somatostatin Signaling Pathway Response To Starvation Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Class A/1 (Rhodopsin-like receptors) Assembly of the primary cilium Metabolic disorders of biological oxidation enzymes BBSome-mediated cargo-targeting to cilium GPCR ligand binding GPCR downstream signaling Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: CORT GNAI1 LNX1 SST TP53
Entrez ID		6753
HPRD ID		01675
Ensembl ID		ENSG00000183473
Uniprot IDs		P32745 Q86YF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Response To Osmotic Stress Synaptic Transmission Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Cell-cell Signaling Negative Regulation Of Helicase Activity G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Hormone-mediated Apoptotic Signaling Pathway Mitochondrial DNA Repair Cell Surface Receptor Signaling Pathway Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence Apoptotic Signaling Pathway ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Blood Coagulation Hemostasis Protein Oligomerization Response To Nutrient Levels Regulation Of Thymocyte Apoptotic Process Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior Response To Extracellular Stimulus Mitochondrial DNA Metabolic Process Positive Regulation Of Histone Deacetylation Rhythmic Behavior Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Protein Oligomerization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process RRNA Transcription Response To Drug
Tagcloud ?		3beta analog catenin colon colonic downregulated elucidated gsk immunocytochemistry inactivated ladder methodology modulation myc numerous octreotide preliminary promoted somatostatin sstr1 sstr2 sstr4 sstr5 sstrs stimulating sw480 tcf wnt