SSTR1 and SSTR5

Number of citations of the paper that reports this interaction (PubMedID 10713101)
0

Data Source:
HPRD (in vitro)

		SSTR1	SSTR5
Description		somatostatin receptor 1	somatostatin receptor 5
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Neuron Projection	Plasma Membrane Membrane Neuron Projection
	Molecular Function	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Protein Binding Neuropeptide Binding	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Protein Binding Neuropeptide Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Glutamate Receptor Signaling Pathway Neuropeptide Signaling Pathway Spermatogenesis Negative Regulation Of Cell Population Proliferation Cerebellum Development Forebrain Development Somatostatin Signaling Pathway Response To Starvation Cellular Response To Estradiol Stimulus Cellular Response To Leukemia Inhibitory Factor	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cytokinesis Somatostatin Signaling Pathway Glucose Homeostasis Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Pasireotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68	Vapreotide Pasireotide Lanreotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS		Chromium levels ( 26025379) Coronary artery aneurysm in Kawasaki disease ( 26434682) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)	Logical memory (immediate recall) in normal cognition ( 29274321) Polycystic ovary syndrome ( 25574032)
Interacting Genes		5 interacting genes: CORT PRMT5 SNTA1 SST SSTR5	9 interacting genes: ADCY10 CNR1 CORT DRD2 GOPC PDZK1 PEX5 SST SSTR1
Entrez ID		6751	6755
HPRD ID		01673	01677
Ensembl ID		ENSG00000139874	ENSG00000162009
Uniprot IDs		P30872 Q86SW9	P35346
PDB IDs		8XIO 8XIP	8X8L 8X8N 8ZBE 8ZCJ
Enriched GO Terms of Interacting Partners?		Somatostatin Signaling Pathway G Protein-coupled Receptor Signaling Pathway Regulation Of Membrane Repolarization Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Receptor Ligand Activity Hormone Activity Transmembrane Transporter Binding Protein-containing Complex Action Potential Syntrophin Complex Hormone-mediated Apoptotic Signaling Pathway Hormone-mediated Signaling Pathway Somatostatin Receptor Activity Positive Regulation Of Protein Kinase A Signaling Histone H4R3 Methyltransferase Activity Peptidyl-arginine N-methylation Positive Regulation Of Dopamine Receptor Signaling Pathway Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Peptidyl-arginine Methylation Response To Steroid Hormone Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Protein Kinase A Signaling Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Monoatomic Cation Transmembrane Transport Junctional Sarcoplasmic Reticulum Membrane Protein-arginine N-methyltransferase Activity Golgi Ribbon Formation Endothelial Cell Activation Regulation Of Monoatomic Ion Transmembrane Transport Nitric-oxide Synthase Binding Adenylate Cyclase Binding Methylosome Regulation Of Dopamine Receptor Signaling Pathway Chemical Synaptic Transmission	G Protein-coupled Receptor Signaling Pathway Somatostatin Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Trans-synaptic Signaling Synaptic Signaling GABA-ergic Synapse Regulation Of Monoatomic Anion Transport Positive Regulation Of Developmental Growth Positive Regulation Of Multicellular Organism Growth Signaling Cell-cell Signaling Telencephalon Cell Migration Positive Regulation Of Growth Forebrain Cell Migration Cell Communication G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Regulation Of Developmental Growth Regulation Of Multicellular Organism Growth Bicarbonate Binding Negative Regulation Of Anion Channel Activity Cannabinoid Receptor Activity G Protein-coupled Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Forebrain Development Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Negative Regulation Of Cardiac Muscle Cell Contraction Neuron Projection Retraction Positive Regulation Of Skeletal Muscle Satellite Cell Differentiation Protein Propionyltransferase Activity Axon Cannabinoid Signaling Pathway Retrograde Trans-synaptic Signaling By Endocannabinoid Synapse Regulation Of Monoatomic Ion Transport Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Regulation Of Protein Localization Negative Regulation Of Dopamine Receptor Signaling Pathway Peroxisome Targeting Sequence Binding Central Region Of Growth Cone Hormone Activity Neuromuscular Process Response To Estradiol Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Dendrite
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