SSTR1

Description		somatostatin receptor 1
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GO Annotations	Cellular Component	Plasma Membrane Membrane Neuron Projection
	Molecular Function	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Protein Binding Neuropeptide Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Glutamate Receptor Signaling Pathway Neuropeptide Signaling Pathway Spermatogenesis Negative Regulation Of Cell Population Proliferation Cerebellum Development Forebrain Development Somatostatin Signaling Pathway Response To Starvation Cellular Response To Estradiol Stimulus Cellular Response To Leukemia Inhibitory Factor
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Pasireotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS		Chromium levels ( 26025379) Coronary artery aneurysm in Kawasaki disease ( 26434682) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
Novel Interacting Genes		1 novel interacting genes: AKAP6
Interacting Genes		5 interacting genes: CORT PRMT5 SNTA1 SST SSTR5
Entrez ID		6751
HPRD ID		01673
Ensembl ID		ENSG00000139874
Uniprot IDs		P30872 Q86SW9
PDB IDs		8XIO 8XIP
Enriched GO Terms of Interacting Partners?		Somatostatin Signaling Pathway G Protein-coupled Receptor Signaling Pathway Regulation Of Membrane Repolarization Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Receptor Ligand Activity Hormone Activity Transmembrane Transporter Binding Protein-containing Complex Action Potential Syntrophin Complex Hormone-mediated Apoptotic Signaling Pathway Hormone-mediated Signaling Pathway Somatostatin Receptor Activity Positive Regulation Of Protein Kinase A Signaling Histone H4R3 Methyltransferase Activity Peptidyl-arginine N-methylation Positive Regulation Of Dopamine Receptor Signaling Pathway Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Peptidyl-arginine Methylation Response To Steroid Hormone Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Protein Kinase A Signaling Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Regulation Of Monoatomic Cation Transmembrane Transport Junctional Sarcoplasmic Reticulum Membrane Protein-arginine N-methyltransferase Activity Golgi Ribbon Formation Endothelial Cell Activation Regulation Of Monoatomic Ion Transmembrane Transport Nitric-oxide Synthase Binding Adenylate Cyclase Binding Methylosome Regulation Of Dopamine Receptor Signaling Pathway Chemical Synaptic Transmission
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