SSTR1

Gene Name		somatostatin receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Somatostatin Receptor Activity Neuropeptide Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Glutamate Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Synaptic Transmission Spermatogenesis Response To Nutrient Digestion Negative Regulation Of Cell Proliferation Cerebellum Development Forebrain Development Somatostatin Signaling Pathway Response To Starvation Cellular Response To Estradiol Stimulus
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Octreotide Pasireotide
Diseases
GWAS		Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
Protein-protein Interactions		5 interactors: CORT PRMT5 SNTA1 SST SSTR5
Entrez ID		6751
HPRD ID		01673
Ensembl ID		ENSG00000139874
Uniprot IDs		P30872 Q86SW9
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Regulation Of Vasoconstriction By Circulating Norepinephrine Hormone-mediated Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Cell-cell Signaling Somatostatin Signaling Pathway Negative Regulation Of Peptidyl-cysteine S-nitrosylation G-protein Coupled Receptor Signaling Pathway Regulation Of Cell Division Hormone-mediated Apoptotic Signaling Pathway Histone H4-R3 Methylation Endothelial Cell Activation Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Peptidyl-arginine N-methylation Response To Steroid Hormone Cellular Response To Estradiol Stimulus Regulation Of Cell Cycle Process Histone Arginine Methylation Ventricular Cardiac Muscle Cell Action Potential Peptidyl-arginine Methylation Regulation Of Membrane Repolarization Hyperosmotic Response Cellular Response To Hormone Stimulus Cardiac Muscle Cell Action Potential Involved In Contraction Cellular Response To Estrogen Stimulus Negative Regulation Of Cell Proliferation Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Regulation Of Cellular Component Movement Positive Regulation Of Cytokinesis Spliceosomal SnRNP Assembly Regulation Of Cardiac Muscle Cell Contraction
Tagcloud ?		3beta analog catenin colon colonic downregulated elucidated gsk immunocytochemistry inactivated ladder methodology modulation myc numerous octreotide preliminary promoted somatostatin sstr2 sstr3 sstr4 sstr5 sstrs stimulating sw480 tcf wnt