SRP54 and SRP19

Number of citations of the paper that reports this interaction (PMID 12244299)
27

Data Source:
HPRD (in vitro)

		SRP54	SRP19
Gene Name		signal recognition particle 54kDa	signal recognition particle 19kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Speck	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol
	Molecular Function	GTPase Activity GTP Binding Drug Binding 7S RNA Binding GDP Binding Endoplasmic Reticulum Signal Peptide Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding	7S RNA Binding Poly(A) RNA Binding
	Biological Process	Translation SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Gene Expression Response To Drug Cellular Protein Metabolic Process Protein Targeting To ER	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Response To Drug Cellular Protein Metabolic Process
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane	Translation SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: RNPS1 SRP19	6 interactors: IPO5 IPO7 IPO8 KPNA1 SRP54 TNPO1
Entrez ID		6729	6728
HPRD ID		05330	01644
Ensembl ID		ENSG00000100883
Uniprot IDs		P61011	P09132
PDB IDs		1MFQ 1QB2	1JID 1MFQ 1RY1 2J37 3KTV
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Intracellular Transport Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Establishment Of Localization In Cell Regulation Of MRNA Processing SRP-dependent Cotranslational Protein Targeting To Membrane Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of RNA Splicing RNA 3'-end Processing Nuclear Export MRNA Transport Protein Localization To Endoplasmic Reticulum Cellular Localization RNA Transport Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Protein Targeting To Membrane RNA Catabolic Process	Intracellular Protein Transport Establishment Of Protein Localization To Organelle Protein Import Into Nucleus Nuclear Import Protein Targeting Protein Import Protein Localization To Organelle Protein Localization To Nucleus Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Cytoplasmic Transport Nucleocytoplasmic Transport Nuclear Transport Protein Localization Establishment Of Localization In Cell Cellular Localization NLS-bearing Protein Import Into Nucleus Viral Process Transport Positive Regulation Of Protein Import Into Nucleus SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Ribosomal Protein Import Into Nucleus Positive Regulation Of Protein Transport Regulation Of Intracellular Transport Apoptotic DNA Fragmentation Intracellular Transport Of Virus Protein Import Into Nucleus, Translocation Apoptotic Nuclear Changes Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Intracellular Protein Transmembrane Transport Cellular Response To Amino Acid Stimulus Regulation Of Protein Localization Protein Transmembrane Transport Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of DNA Recombination Execution Phase Of Apoptosis Response To Stimulus
Tagcloud ?		abrupt bip cerevisiae coincident cytoplasmic depleted disulfide doublings drastically fall foldase hann homolog hsp104 hsp70 hsp82 isomerase participate precursors resident saccharomyces secretory slowing stressors unlike untranslocated walter ydj1p	5q22 adjusted apc caner chose cnv copy discovering exon9 fluorophores gastric integer interrogate intron8 losses obtain original platform probe probes reep5 searched sought surrounding taqman transformed variation volunteers yielded
Tagcloud (Difference) ?		abrupt bip cerevisiae coincident cytoplasmic depleted disulfide doublings drastically fall foldase hann homolog hsp104 hsp70 hsp82 isomerase participate precursors resident saccharomyces secretory slowing stressors unlike untranslocated walter ydj1p	5q22 adjusted apc caner chose cnv copy discovering exon9 fluorophores gastric integer interrogate intron8 losses obtain original platform probe probes reep5 searched sought surrounding taqman transformed variation volunteers yielded
Tagcloud (Intersection) ?