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SRP54

Description signal recognition particle 54
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleolus
  • Cytoplasm
  • Endoplasmic Reticulum
  • Signal Recognition Particle, Endoplasmic Reticulum Targeting
  • Cytosol
  • Nuclear Speck
  • Signal Recognition Particle
  • Ribonucleoprotein Complex
Molecular Function
  • Nucleotide Binding
  • RNA Binding
  • GTPase Activity
  • Protein Binding
  • GTP Binding
  • 7S RNA Binding
  • Hydrolase Activity
  • GDP Binding
  • Endoplasmic Reticulum Signal Peptide Binding
  • Ribonucleoprotein Complex Binding
Biological Process
  • SRP-dependent Cotranslational Protein Targeting To Membrane
  • SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation
  • SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition
  • Neutrophil Chemotaxis
  • Granulocyte Differentiation
  • Exocrine Pancreas Development
  • Protein Targeting To ER
Pathways
  • SRP-dependent cotranslational protein targeting to membrane
  • SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS
  • Heel bone mineral density ( 30598549)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Novel Interacting Genes 6 novel interacting genes: EGLN3 KLK12 PRORP RALGAPA1 STAB1 TKTL1
Interacting Genes 4 interacting genes: CEBPA OGT RNPS1 SRP19
Entrez ID 6729
HPRD ID 05330
Ensembl ID ENSG00000100883
Uniprot IDs G3V480 P61011
PDB IDs 1MFQ 1QB2 5L3Q 6Y2Z 6Y30 6Y31 6Y32 7NFX 7QWQ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025