SRP54

Gene Name		signal recognition particle 54kDa
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Speck
	Molecular Function	GTPase Activity GTP Binding Drug Binding 7S RNA Binding GDP Binding Endoplasmic Reticulum Signal Peptide Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding
	Biological Process	Translation SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Gene Expression Response To Drug Cellular Protein Metabolic Process Protein Targeting To ER
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: RNPS1 SRP19
Entrez ID		6729
HPRD ID		05330
Ensembl ID		ENSG00000100883
Uniprot IDs		P61011
PDB IDs		1MFQ 1QB2
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Intracellular Transport Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Establishment Of Localization In Cell Regulation Of MRNA Processing SRP-dependent Cotranslational Protein Targeting To Membrane Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of RNA Splicing RNA 3'-end Processing Nuclear Export MRNA Transport Protein Localization To Endoplasmic Reticulum Cellular Localization RNA Transport Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Protein Targeting To Membrane RNA Catabolic Process
Tagcloud ?		abrupt bip cerevisiae coincident cytoplasmic depleted disulfide doublings drastically fall foldase hann homolog hsp104 hsp70 hsp82 isomerase participate precursors resident saccharomyces secretory slowing stressors unlike untranslocated walter ydj1p