SRP19 and AP3S1

		SRP19	AP3S1
Description		signal recognition particle 19	adaptor related protein complex 3 subunit sigma 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Body Signal Recognition Particle Ribonucleoprotein Complex	Early Endosome Golgi Apparatus Membrane Membrane Coat AP-type Membrane Coat Adaptor Complex AP-3 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Presynapse Axon Cytoplasm
	Molecular Function	RNA Binding Protein Binding 7S RNA Binding Ribosome Binding	Protein Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition	Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Insulin Receptor Signaling Pathway Protein Transport Synaptic Vesicle Coating Vesicle-mediated Transport Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Synaptic Vesicle Recycling Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Melanosome Assembly
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: APP CEBPA IPO5 IPO7 IPO8 KPNA1 MAPK8IP2 SRP54 TNPO1	7 interacting genes: AP3B2 AP3D1 AP3S2 IRS1 RUFY1 SCARB2 SLC30A3
Entrez ID		6728	1176
HPRD ID		01644	03298
Ensembl ID		ENSG00000153037	ENSG00000177879
Uniprot IDs		A0A087WYR0 A0A2U3TZN1 P09132	F5H459 Q92572
PDB IDs		1JID 1MFQ 1RY1 2J37 3KTV 4P3E 5M73 7NFX 7QWQ	9C58 9C59 9C5B 9C5C
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Protein Import Into Nucleus Import Into Nucleus Establishment Of Protein Localization To Organelle Protein Localization To Nucleus Intracellular Transport Nuclear Transport Nucleocytoplasmic Transport Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding Cellular Localization Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization Nuclear Pore Small GTPase Binding Intracellular Protein Localization Protein Localization To Organelle Mating Behavior NLS-bearing Protein Import Into Nucleus Regulation Of Protein Localization To Nucleus Granulocyte Differentiation Reproductive Behavior Modulation Of Excitatory Postsynaptic Potential Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Learning Or Memory Amylin Binding Positive Regulation Of Toll Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cognition Protein-containing Complex Acetylcholine Receptor Activator Activity Axo-dendritic Transport Lipoprotein Particle Positive Regulation Of Protein Import Negative Regulation Of Cell Cycle Response To Vitamin B2 C/EBP Complex Positive Regulation Of Viral Translation Regulation Of Defense Response PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development	Synaptic Vesicle Coating Clathrin-coated Vesicle Cargo Loading, AP-3-mediated AP-3 Adaptor Complex Anterograde Synaptic Vesicle Transport Synaptic Vesicle Recycling Membrane Coat Cellular Localization Vesicle Cargo Loading Synaptic Vesicle Transport Vesicle Coating Vacuolar Transport Anterograde Axonal Transport Vesicle Transport Along Microtubule Zinc Ion Import Into Lysosome Vesicle Cytoskeletal Trafficking Intracellular Transport Axon Cytoplasm Axonal Transport Establishment Of Protein Localization Vacuolar Transmembrane Transport Axo-dendritic Transport Organelle Transport Along Microtubule Vesicle Organization Zinc Ion Import Into Organelle Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Localization Lysosomal Transport Melanosome Assembly Intracellular Membrane-bounded Organelle Golgi To Vacuole Transport Protein Transport Platelet Dense Granule Organization Transport Along Microtubule Intracellular Protein Transport Zinc Ion Transmembrane Transport Vesicle-mediated Transport Zinc Ion Transport Cytoskeleton-dependent Intracellular Transport Protein Targeting Microtubule-based Transport Melanosome Organization Pigment Granule Organization SH2 Domain Binding Establishment Of Organelle Localization Golgi Vesicle Transport Protein Targeting To Vacuole Protein Localization To Lysosome Regulation Of Lipid Catabolic Process Early Endosome
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