SH3GL3 and FAM173A

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SH3GL3	FAM173A
Gene Name		SH3-domain GRB2-like 3	family with sequence similarity 173, member A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Membrane Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Endocytosis Signal Transduction Central Nervous System Development
Pathways
Drugs
Diseases
GWAS		Height ( 18391950 18391951 20397748)
Protein-Protein Interactions		44 interactors: ADRB1 AES ARHGDIA ARHGEF6 ATXN2 C11orf68 C4orf17 CALCOCO1 CBLC CD101 CRIP1 DNM1 DPPA4 DPYSL4 EGFL6 EMD FAM173A FASLG GABBR2 HTT LRRK2 NDUFB9 PDCD6IP PIAS4 PTPRO QTRT1 RBM48 RER1 RPL35A SEPT8 SH3D19 SH3GL1 SH3GL2 SH3KBP1 SHC3 SNRPN SNX24 SYNJ1 TERF1 TNNT1 TOE1 VIM WASL WDR33	9 interactors: BAG6 HAP1 IMMT KAT5 LUC7L LUC7L2 PFN2 SH3GL3 TP53
Entrez ID		6457	65990
HPRD ID		04528	14500
Ensembl ID		ENSG00000140600	ENSG00000103254
Uniprot IDs		Q99963	J3KMW5 Q9BQD7
PDB IDs		2EW3 2Z0V
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Signaling Regulation Of ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell-cell Signaling Signal Transduction Vesicle-mediated Transport Cell Communication Movement Of Cell Or Subcellular Component Regulation Of Vesicle-mediated Transport Response To Stimulus Cellular Response To Stimulus Cell Death Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Membrane Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Negative Regulation Of ERBB Signaling Pathway Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Developmental Process System Development Neuron Development Apoptotic Process Cellular Process Generation Of Neurons Actin Filament-based Movement Multicellular Organismal Development Nervous System Development Programmed Cell Death Regulation Of Signaling Neurogenesis Regulation Of Endocytosis Regulation Of Signal Transduction Negative Regulation Of Neuron Differentiation Neuron Projection Development Establishment Of Vesicle Localization Synaptic Transmission Positive Regulation Of Apoptotic Process Cell Projection Morphogenesis Neuron Differentiation Vesicle Localization Response To Growth Factor Axon Guidance Neurotrophin TRK Receptor Signaling Pathway Cell Part Morphogenesis	Signal Transduction By P53 Class Mediator DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Double-strand Break Repair Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator MRNA Splice Site Selection Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Cellular Response To DNA Damage Stimulus Positive Regulation Of Cellular Component Biogenesis Spliceosomal Complex Assembly Base-excision Repair Central Nervous System Development Chromosome Organization Positive Regulation Of Organelle Organization DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Signal Transduction In Response To DNA Damage Nucleotide-excision Repair Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Protein Metabolic Process Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Cerebellum Development Regulation Of Cell Projection Assembly Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Metencephalon Development Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Acetylation Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cilium Assembly Negative Regulation Of Helicase Activity Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity DNA Repair Response To Ionizing Radiation Regulation Of Exocytosis Response To Endoplasmic Reticulum Stress Cellular Response To Stress Ribonucleoprotein Complex Assembly Hindbrain Development Positive Regulation Of Protein Complex Assembly Chromatin Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Thymocyte Apoptotic Process Negative Regulation Of Ruffle Assembly Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cell Aging
Tagcloud ?		85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Difference) ?		85k aorta cbl cin85 circulation circulatory cooperation da diameters dorsal endocytosis exerted impairing interacting lumen lumens morpholino morpholinos partner phosphatidylinositol shrinkage shrunken specification stereotyped studying unaffected vasculature zebrafish
Tagcloud (Intersection) ?