DMTN

Description		dematin actin binding protein
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GO Annotations	Cellular Component	Cytoplasm Smooth Endoplasmic Reticulum Cytosol Cytoskeleton Actin Filament Plasma Membrane Endomembrane System Postsynaptic Density Spectrin-associated Cytoskeleton Actin Cytoskeleton Membrane Cortical Cytoskeleton Platelet Dense Tubular Network Membrane Cell Projection Membrane Cytoplasmic Vesicle Cell Projection Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Signaling Receptor Binding Protein Binding Spectrin Binding Actin Filament Binding
	Biological Process	Cytoskeleton Organization Regulation Of Cell Shape Regulation Of Lamellipodium Assembly Positive Regulation Of Fibroblast Migration Negative Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Cell-substrate Adhesion Lamellipodium Assembly Actin Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Peptidyl-serine Phosphorylation Erythrocyte Development Negative Regulation Of Peptidyl-tyrosine Phosphorylation Actin Filament Bundle Assembly Regulation Of Filopodium Assembly Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Actin Filament Capping Negative Regulation Of Focal Adhesion Assembly Protein-containing Complex Assembly Cellular Response To CAMP Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Wound Healing Negative Regulation Of Protein Targeting To Membrane Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Apolipoprotein B levels ( 32203549) Gamma glutamyl transferase levels ( 33339817) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Total cholesterol levels ( 30275531)
Interacting Genes		16 interacting genes: ACTB ACTC1 APP CEP76 DYNC1LI2 EPB42 GOLGA2 NEDD4L PRKACA PROCR PTOV1 SNCA SNRPD2 SPTB TEX11 TRAF2
Entrez ID		2039
HPRD ID		00506
Ensembl ID		ENSG00000158856
Uniprot IDs		Q08495
PDB IDs		1QZP 1ZV6
Enriched GO Terms of Interacting Partners?		Regulation Of Norepinephrine Uptake Transporter Regulator Activity Regulation Of Endocytosis Positive Regulation Of Endocytosis Cytoskeleton Protein-containing Complex Cell Junction Organization Postsynapse Cellular Response To Epinephrine Stimulus Positive Regulation Of Transport Cellular Component Assembly Protein Tetramerization Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Response To Epinephrine Structural Constituent Of Cytoskeleton Actin Cytoskeleton Regulation Of Vesicle-mediated Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Neurotransmitter Uptake Cytoplasm Cytoskeleton Organization Cellular Response To Copper Ion Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Regulation Of Metal Ion Transport Regulation Of Generation Of Precursor Metabolites And Energy Cortical Cytoskeleton Regulation Of Synaptic Vesicle Recycling Regulation Of Calcium Ion Transmembrane Transport Perinuclear Region Of Cytoplasm Regulation Of Protein Catabolic Process Amyloid Fibril Formation Microglial Cell Activation Negative Regulation Of Catabolic Process Cell Maturation Positive Regulation Of Small Molecule Metabolic Process Leukocyte Activation Involved In Inflammatory Response Response To Copper Ion Regulation Of Monoatomic Ion Transport Inorganic Ion Homeostasis Cell Cortex Regulation Of Cellular Component Organization Kinesin Binding Protein Kinase Binding Tau Protein Binding Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Amyloid-beta Complex
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