SNRPA1 and SNRPB2

Number of citations of the paper that reports this interaction (PMID 9716128)
89

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SNRPA1	SNRPB2
Gene Name		small nuclear ribonucleoprotein polypeptide A	small nuclear ribonucleoprotein polypeptide B
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U2 SnRNP Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex U2 SnRNP Nucleolus Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Nucleotide Binding Protein Binding SnRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: NCBP1 SNRPA SNRPB2 SNRPF	16 interactors: CALM1 DHX9 GABPB1 GOLGA2 HMBOX1 HNRNPUL1 HOMEZ HTATSF1 MCM6 MTUS2 PNMA1 SMN2 SNRPA1 SUGP1 TRIM27 ZBTB14
Entrez ID		6627	6629
HPRD ID		04629	04628
Ensembl ID		ENSG00000131876	ENSG00000125870
Uniprot IDs		P09661	P08579
PDB IDs		1A9N	1A9N
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Histone MRNA Metabolic Process Termination Of RNA Polymerase II Transcription Spliceosomal SnRNP Assembly DNA-templated Transcription, Termination MRNA 3'-end Processing RNA 3'-end Processing Ribonucleoprotein Complex Assembly RNA Metabolic Process Gene Expression Ribonucleoprotein Complex Biogenesis Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process NcRNA Metabolic Process MRNA Cis Splicing, Via Spliceosome Positive Regulation Of MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing Nitrogen Compound Metabolic Process MRNA Cleavage Cellular Macromolecular Complex Assembly 7-methylguanosine MRNA Capping 7-methylguanosine RNA Capping Positive Regulation Of Viral Transcription Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Silencing By RNA MRNA Export From Nucleus Regulation Of Viral Transcription Positive Regulation Of Viral Process Regulation Of Translational Initiation RNA Export From Nucleus DNA-templated Transcription, Elongation Regulation Of MRNA Processing Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Gene Silencing MRNA Transport Nuclear Export RNA Transport	RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Processing MRNA Metabolic Process RNA Processing Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA Duplex Unwinding DNA Geometric Change Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Ion Transport Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity CRD-mediated MRNA Stabilization Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Calcium Ion Import Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Nitrogen Compound Metabolic Process Interferon-gamma Secretion Regulation Of Calcium Ion Transport Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Immune Response Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Detection Of Calcium Ion Defense Response Negative Regulation Of Biosynthetic Process Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity DNA Unwinding Involved In DNA Replication
Tagcloud ?			acetyltransferase aggregates als amyotrophic anacardic candidates carry cytoskeletal cytosolic degenerate detergent elucidating familial fatal generate hampered insoluble ipsc ipscs motor neurites neuron neurons pluripotent postmortem rescued spliceosomal tar zebrafish
Tagcloud (Difference) ?			acetyltransferase aggregates als amyotrophic anacardic candidates carry cytoskeletal cytosolic degenerate detergent elucidating familial fatal generate hampered insoluble ipsc ipscs motor neurites neuron neurons pluripotent postmortem rescued spliceosomal tar zebrafish
Tagcloud (Intersection) ?