SNAPC1 and NR2E3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		SNAPC1	NR2E3
Description		small nuclear RNA activating complex polypeptide 1	nuclear receptor subfamily 2 group E member 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus SnRNA-activating Protein Complex	Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Sequence-specific DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Steroid Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Signal Transduction Visual Perception Phototransduction Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Neuron Differentiation Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Positive Regulation Of Transcription By RNA Polymerase II Retina Development In Camera-type Eye
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases			Retinitis pigmentosa (RP) Vitreoretinal degeneration, including: Stickler syndrome type I (STL1); Stickler syndrome type II (STL2); Snowflake vitreoretinal degeneration (SVD); Wagner syndrome 1 (WGN1); Knobloch syndrome (KNO); Enhanced S-cone syndrome (ESCS); Autosomal dominant vitreoretinochoroidopathy (ADVIRC)
GWAS		Chronotype ( 30696823) Metabolite levels ( 23823483)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Macular thickness ( 30535121) Metabolite levels (HVA/MHPG ratio) ( 23319000) Red blood cell count ( 32888494)
Interacting Genes		14 interacting genes: CCDC6 EXOC8 HAT1 HOXA10 HSF2BP NR2E3 RB1 RHOXF2 SAAL1 SNAPC3 SNAPC4 SNAPC5 TBP TRIM29	29 interacting genes: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 NRL POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 WDR5 ZNF232
Entrez ID		6617	10002
HPRD ID		08998	05132
Ensembl ID		ENSG00000023608	ENSG00000278570
Uniprot IDs		B2RC42 Q16533	F1D8Q9 Q9Y5X4
PDB IDs		7XUR 7ZWC 7ZWD 7ZX7 7ZX8 7ZXE 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS	4LOG
Enriched GO Terms of Interacting Partners?		RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III SnRNA Transcription By RNA Polymerase III Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase II SnRNA Transcription DNA-templated Transcription SnRNA-activating Protein Complex RNA Polymerase II General Transcription Initiation Factor Activity SnRNA Metabolic Process RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Nucleobase-containing Compound Biosynthetic Process Core Promoter Sequence-specific DNA Binding Nucleoplasm Male Gamete Generation Spermatogenesis RNA Metabolic Process Macromolecule Biosynthetic Process DNA Binding Gamete Generation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Regulator Complex Chromatin Bent DNA Binding DNA-templated Transcription Initiation Chromatin Lock Complex Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity Positive Regulation Of Collagen Fibril Organization TFIIB-class Transcription Factor Binding Positive Regulation Of Synoviocyte Proliferation Nucleic Acid Metabolic Process	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Cis-regulatory Region Binding Nucleus Positive Regulation Of RNA Metabolic Process Histone Deacetylase Complex Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nuclear Receptor Activity Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Chromatin Binding Hormone-mediated Signaling Pathway DNA-binding Transcription Factor Activity Negative Regulation Of Macromolecule Metabolic Process Transcription By RNA Polymerase II Sequence-specific Double-stranded DNA Binding DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Sin3-type Complex Chromatin Organization Retinoic Acid Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Metabolic Process Retinoic Acid-responsive Element Binding Nucleic Acid Metabolic Process
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