SNAPC1 and HOXA10

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		SNAPC1	HOXA10
Description		small nuclear RNA activating complex polypeptide 1	homeobox A10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus SnRNA-activating Protein Complex	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Sequence-specific DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Histone Deacetylase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III	Skeletal System Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Spermatogenesis Single Fertilization Male Gonad Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Regulation Of Gene Expression Embryonic Limb Morphogenesis Prostate Gland Development Response To Testosterone Response To Estrogen Positive Regulation Of Transcription By RNA Polymerase II Uterus Development
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs			Calcitriol
Diseases
GWAS		Chronotype ( 30696823) Metabolite levels ( 23823483)	Dental caries ( 23259602) Hypertension ( 30487518 31879980) Mean arterial pressure ( 30487518) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		14 interacting genes: CCDC6 EXOC8 HAT1 HOXA10 HSF2BP NR2E3 RB1 RHOXF2 SAAL1 SNAPC3 SNAPC4 SNAPC5 TBP TRIM29	14 interacting genes: CREBBP EMX1 EP300 FOXO1 GMNN GNG13 HMGB1 MEIS1 PBX1 POLR3D PTPN6 SIRT2 SNAPC1 SPI1
Entrez ID		6617	3206
HPRD ID		08998	00845
Ensembl ID		ENSG00000023608	ENSG00000253293
Uniprot IDs		B2RC42 Q16533	P31260
PDB IDs		7XUR 7ZWC 7ZWD 7ZX7 7ZX8 7ZXE 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III SnRNA Transcription By RNA Polymerase III Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase II SnRNA Transcription DNA-templated Transcription SnRNA-activating Protein Complex RNA Polymerase II General Transcription Initiation Factor Activity SnRNA Metabolic Process RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Nucleobase-containing Compound Biosynthetic Process Core Promoter Sequence-specific DNA Binding Nucleoplasm Male Gamete Generation Spermatogenesis RNA Metabolic Process Macromolecule Biosynthetic Process DNA Binding Gamete Generation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Regulator Complex Chromatin Bent DNA Binding DNA-templated Transcription Initiation Chromatin Lock Complex Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity Positive Regulation Of Collagen Fibril Organization TFIIB-class Transcription Factor Binding Positive Regulation Of Synoviocyte Proliferation Nucleic Acid Metabolic Process	DNA-binding Transcription Factor Binding Chromatin Binding Positive Regulation Of Innate Immune Response Histone H3K27 Acetyltransferase Activity Megakaryocyte Development Regulation Of Innate Immune Response Positive Regulation Of Defense Response Transcription Regulator Complex Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Nucleus Protein Acetylation Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Developmental Process Positive Regulation Of Binding Regulation Of Oligodendrocyte Progenitor Proliferation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Hemopoiesis Positive Regulation Of Immune Response RNA Polymerase II-specific DNA-binding Transcription Factor Binding Chromatin Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Regulation Of Immune System Process Damaged DNA Binding Transcription Corepressor Activity Regulation Of RNA Metabolic Process Activation Of Innate Immune Response Developmental Process Myeloid Cell Development Regulation Of Cell Differentiation Regulation Of Hemopoiesis Negative Regulation Of Cell-cell Adhesion Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Lymphocyte Differentiation STAT Family Protein Binding Regulation Of Cell Population Proliferation Lymphocyte Activation Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process
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