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FAM173A and KAT5
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
FAM173A
KAT5
Gene Name
family with sequence similarity 173, member A
K(lysine) acetyltransferase 5
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Membrane
Swr1 Complex
Nucleus
Nucleoplasm
Transcription Factor Complex
Nucleolus
Cytosol
Piccolo NuA4 Histone Acetyltransferase Complex
NuA4 Histone Acetyltransferase Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Transcription Coactivator Activity
Histone Acetyltransferase Activity
Protein Binding
Protein Complex Binding
Metal Ion Binding
Androgen Receptor Binding
Repressing Transcription Factor Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Double-strand Break Repair
Chromatin Organization
Transcription, DNA-templated
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Response To Ionizing Radiation
Viral Process
Histone Acetylation
Androgen Receptor Signaling Pathway
Negative Regulation Of Interleukin-2 Production
Regulation Of Growth
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Estradiol Stimulus
Positive Regulation Of Protein Acetylation
Pathways
Chromatin modifying enzymes
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
TCF dependent signaling in response to WNT
RNF mutants show enhanced WNT signaling and proliferation
formation of the beta-catenin:TCF transactivating complex
XAV939 inhibits tankyrase, stabilizing AXIN
Signaling by Wnt
Signaling by WNT in cancer
HATs acetylate histones
Drugs
Diseases
GWAS
Chronic kidney disease (
20383146
)
Protein-Protein Interactions
9 interactors:
BAG6
HAP1
IMMT
KAT5
LUC7L
LUC7L2
PFN2
SH3GL3
TP53
136 interactors:
ALOX12
APBB1
APLP1
APLP2
APP
AR
ARIH2
ATM
ATXN1
BARD1
BCL3
BMI1
BRCA1
C1orf174
CBX8
CCDC106
CCDC136
CCNB1
CCT7
CDC42
CDK1
CDK5RAP2
CDKN2A
CREB1
CREBBP
CRELD1
CSTF2
DLEU1
DUSP23
E2F1
EDNRA
EFNA1
EP300
ESR1
ESR2
ETV6
FAM101B
FAM135B
FAM173A
GADD45G
GAPDH
GEMIN7
GET4
GMCL1
GMCL1P1
GOLGA2
GSTO1
H2AFX
H3F3B
HABP4
HAP1
HDAC1
HDAC7
HIST1H3A
HIST1H4A
HIST2H2AC
HIST2H3C
HIST2H4A
HIST3H3
HMBOX1
HNRNPH3
IK
IKZF3
IL9R
KIAA1377
KLF4
KRT40
KRTAP10-3
KRTAP10-9
LMNA
LONRF1
LRIF1
LRP1
LZTS2
MAD2L1BP
MAPRE1
MDFI
MDM2
MEOX2
MTUS2
MYC
MYOD1
NAP1L5
NDUFA4L2
NDUFV2
NFKB1
NINL
NR3C1
ODC1
OGFOD2
PDCD5
PHC2
PIH1D3
PITX2
PLA2G4A
PLEKHA4
PML
POLE2
POLR3F
PPARG
PTPN4
PTPRS
RB1
RCHY1
RELA
RGL2
RRM1
RRM2
SAT1
SNAPIN
SNRPD2
SOX5
SRF
SSX2IP
STAT3
STX11
SYN1
TBX5
TELO2
TMCC2
TNNT1
TP53
TRIB3
TRIM23
TRIM27
TRIM29
TRIM37
TUFT1
UHRF1
USP7
YWHAG
ZBTB14
ZBTB8A
ZEB1
ZNF24
ZNF513
Entrez ID
65990
10524
HPRD ID
14500
03245
Ensembl ID
ENSG00000103254
ENSG00000172977
Uniprot IDs
J3KMW5
Q9BQD7
Q92993
PDB IDs
2EKO
2OU2
Enriched GO Terms of Interacting Partners
?
Signal Transduction By P53 Class Mediator
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
DNA Damage Response, Signal Transduction Resulting In Transcription
Double-strand Break Repair
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
MRNA Splice Site Selection
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Cellular Component Biogenesis
Spliceosomal Complex Assembly
Base-excision Repair
Central Nervous System Development
Chromosome Organization
Positive Regulation Of Organelle Organization
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Nonmotile Primary Cilium Assembly
Signal Transduction In Response To DNA Damage
Nucleotide-excision Repair
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Regulation Of Protein Metabolic Process
Negative Regulation Of Macromitophagy
Oligodendrocyte Apoptotic Process
Cerebellum Development
Regulation Of Cell Projection Assembly
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Metencephalon Development
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Protein Acetylation
Regulation Of Cell Cycle G1/S Phase Transition
Positive Regulation Of Cilium Assembly
Negative Regulation Of Helicase Activity
Regulation Of Organelle Transport Along Microtubule
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
DNA Repair
Response To Ionizing Radiation
Regulation Of Exocytosis
Response To Endoplasmic Reticulum Stress
Cellular Response To Stress
Ribonucleoprotein Complex Assembly
Hindbrain Development
Positive Regulation Of Protein Complex Assembly
Chromatin Organization
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Thymocyte Apoptotic Process
Negative Regulation Of Ruffle Assembly
Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Positive Regulation Of Cell Aging
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Transcription, DNA-templated
Gene Expression
Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
RNA Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Developmental Process
Organ Development
Regulation Of Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Multicellular Organismal Development
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Chromatin Organization
Positive Regulation Of Metabolic Process
Mitotic Cell Cycle
Chromosome Organization
Anatomical Structure Development
Cellular Macromolecule Biosynthetic Process
System Development
Tissue Development
Cell Cycle
Macromolecule Biosynthetic Process
Regulation Of Cell Proliferation
Cell Death
Apoptotic Process
Death
Organelle Organization
Programmed Cell Death
Biosynthetic Process
Tagcloud
?
accumbens
brn2
decondensed
dmnt1
dnmt3a
erg1
exceptionally
fox3
foxg1
gadd45a
gadd45b
hdac11
homer1
kat2b
kat3a
kat3b
multilineage
multipotent
nef1
neg
neun
neurobiol
neurobiology
neuroplasticity
nfl
nuclei
periodicals
pons
syt1
Tagcloud (Difference)
?
accumbens
brn2
decondensed
dmnt1
dnmt3a
erg1
exceptionally
fox3
foxg1
gadd45a
gadd45b
hdac11
homer1
kat2b
kat3a
kat3b
multilineage
multipotent
nef1
neg
neun
neurobiol
neurobiology
neuroplasticity
nfl
nuclei
periodicals
pons
syt1
Tagcloud (Intersection)
?