ZBTB49

Description		zinc finger and BTB domain containing 49
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444)
Interacting Genes		12 interacting genes: CEP70 CIB1 EP300 GOPC PICK1 POT1 TP53 TRAF2 TRAF3 VAC14 ZBTB2 ZBTB8A
Entrez ID		166793
HPRD ID		10335
Ensembl ID		ENSG00000168826
Uniprot IDs		Q6ZSB9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-binding Transcription Factor Activity Transcription Coactivator Binding Identical Protein Binding Tumor Necrosis Factor-mediated Signaling Pathway Thioesterase Binding CD40 Receptor Complex Regulation Of Cellular Component Organization TORC2 Signaling Positive Regulation Of DNA-binding Transcription Factor Activity Apoptotic Signaling Pathway Regulation Of Organelle Organization Negative Regulation Of Cellular Component Organization Programmed Necrotic Cell Death Negative Regulation Of Telomere Maintenance Via Telomerase Platelet Formation Cytokine-mediated Signaling Pathway Apoptotic Process T Cell Lineage Commitment Intrinsic Apoptotic Signaling Pathway Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Tumor Necrosis Factor Receptor Binding Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Programmed Cell Death Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cell Death RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Telomere Maintenance Positive Regulation Of Gene Expression, Epigenetic Regulation Of Phosphorus Metabolic Process Somitogenesis Peptidyl-lysine Propionylation Segmentation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Transcription Initiation-coupled Chromatin Remodeling Histone Butyryltransferase Activity Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Nutrient Levels Histone Crotonyltransferase Activity Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Cellular Response To Glucose Starvation Regulation Of Telomere Maintenance Via Telomere Lengthening TORC2 Complex Disassembly
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