UBE2Z and AK8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		UBE2Z	AK8
Gene Name		ubiquitin-conjugating enzyme E2Z	adenylate kinase 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cytosol
	Molecular Function	Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	Adenylate Kinase Activity Cytidylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process	Nucleoside Diphosphate Phosphorylation Nucleoside Triphosphate Biosynthetic Process Ventricular System Development
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS		Coronary heart disease ( 21378990)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		31 interactors: AK8 BMPR1B DZIP3 HLTF HMBOX1 LNX2 LPL MDM2 PLEKHF2 PPP1CA RAPSN REL RNF103 RNF130 RNF139 RNF144B RNF150 RNF166 RNF41 RNF5 SMAD1 SMAD4 SRA1 SYVN1 TGFBR1 TRAIP TRIM27 TRIM46 TRIM65 UBA6 UBD	10 interactors: ALKBH3 CCDC102B HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 RBM39 UBE2Z ZMAT2
Entrez ID		65264	158067
HPRD ID		08589	12991
Ensembl ID		ENSG00000159202	ENSG00000165695
Uniprot IDs		Q9H832	Q96MA6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Metabolic Process Protein Catabolic Process Regulation Of Cell Death Cellular Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Polyubiquitination Cellular Macromolecule Catabolic Process Protein Destabilization Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway ER-associated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Apoptotic Process Endothelial Cell Activation Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of SMAD Protein Import Into Nucleus Apoptotic Process Negative Regulation Of Cell Proliferation SMAD Protein Complex Assembly BMP Signaling Pathway Regulation Of SMAD Protein Import Into Nucleus Programmed Cell Death Cell Death Death Regulation Of Cartilage Development Response To Stress Proteasomal Protein Catabolic Process Proteolysis Triglyceride Catabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Gene Expression Regulation Of Signaling Cardiac Epithelial To Mesenchymal Transition Acylglycerol Catabolic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Response To Growth Factor Negative Regulation Of Gene Expression Positive Regulation Of Programmed Cell Death Metabolic Process	Histone H3-R2 Methylation Oxidative Single-stranded DNA Demethylation
Tagcloud ?		array c9orf72 carriers conjugating consisting deregulation discovery displays encode except expansion frontotemporal ftd generalized grn matched preliminary proteasomal proteasome sabiosciences sporadic statistically ube2e1 ube2i ube2n ube2q1 ubiquitin ubiquitination
Tagcloud (Difference) ?		array c9orf72 carriers conjugating consisting deregulation discovery displays encode except expansion frontotemporal ftd generalized grn matched preliminary proteasomal proteasome sabiosciences sporadic statistically ube2e1 ube2i ube2n ube2q1 ubiquitin ubiquitination
Tagcloud (Intersection) ?