AK8 and CDK18

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AK8	CDK18
Description		adenylate kinase 8	cyclin dependent kinase 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Axoneme Sperm Flagellum Cell Projection 9+2 Motile Cilium	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Nucleotide Binding AMP Kinase Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding AMP Binding Kinase Activity Transferase Activity Phosphotransferase Activity, Phosphate Group As Acceptor Nucleobase-containing Compound Kinase Activity DCMP Kinase Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Nucleotide Metabolic Process Nucleoside Monophosphate Metabolic Process Ventricular System Development Nucleoside Monophosphate Phosphorylation	Positive Regulation Of Myelination Regulation Of Cell Cycle Phase Transition
Pathways		Interconversion of nucleotide di- and triphosphates
Drugs		Bis(Adenosine)-5'-Pentaphosphate
Diseases
GWAS		Obesity-related traits ( 23251661)	Coronary artery disease in type 1 diabetes ( 29695241)
Interacting Genes		17 interacting genes: ALKBH3 CCDC102B CDK18 CFTR CNTF DPY30 FBXO7 HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 RBM39 SMG9 SYT17 UBE2Z ZMAT2	55 interacting genes: AK8 APP BLZF1 CBY2 CCDC102B CCDC125 CCDC85B CCDC88B CCND3 CCNDBP1 CCNK CEP76 EYA2 FSD2 GOLGA2 GOLGA6L9 GORASP2 HAP1 HMBOX1 HOMER3 HOOK2 INCA1 KIFC3 KRT15 KRT16 KRT31 KRT34 KRT40 KRT75 KRT86 LZTS2 MAD1L1 MID2 MIPOL1 MTUS2 NUTM1 PIBF1 PNMA1 PPFIA1 RABEP1 REL SEC23A TRAF1 TRAF2 TRIM27 TRIM50 TRIM54 TSGA10 TTC23 VPS28 VPS52 ZNF426 ZNF438 ZNF774 ZRANB1
Entrez ID		158067	5129
HPRD ID		12991	01354
Ensembl ID		ENSG00000165695	ENSG00000117266
Uniprot IDs		Q96MA6	Q07002 Q59G02
PDB IDs
Enriched GO Terms of Interacting Partners?			Cytoskeleton Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Supramolecular Fiber Organization Intermediate Filament Cytoskeleton Organization Centrosome Microtubule Protein Binding Microtubule Binding Cytoplasm Structural Molecule Activity Organelle Organization Microtubule-based Process Dynein Light Intermediate Chain Binding Identical Protein Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Cytosol Cellular Localization Thioesterase Binding Cis-Golgi Network Golgi Organization Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
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