AK8 and ALKBH3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AK8	ALKBH3
Gene Name		adenylate kinase 8	alkB, alkylation repair homolog 3 (E. coli)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Cytoplasm Mitochondrion
	Molecular Function	Adenylate Kinase Activity Cytidylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding	Protein Binding Ferrous Iron Binding L-ascorbic Acid Binding DNA-N1-methyladenine Dioxygenase Activity Cytosine C-5 DNA Demethylase Activity
	Biological Process	Nucleoside Diphosphate Phosphorylation Nucleoside Triphosphate Biosynthetic Process Ventricular System Development	DNA Repair DNA Dealkylation Involved In DNA Repair Cell Proliferation Oxidative Single-stranded DNA Demethylation
Pathways			ABH3 mediated Reversal of Alkylation Damage DNA Damage Reversal Reversal of Alkylation Damage By DNA Dioxygenases
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		10 interactors: ALKBH3 CCDC102B HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 RBM39 UBE2Z ZMAT2	8 interactors: AK8 GLRX3 GOLGA2 IKZF1 LNX1 SRPK1 SRPK2 ZDHHC17
Entrez ID		158067	221120
HPRD ID		12991	16793
Ensembl ID		ENSG00000165695	ENSG00000166199
Uniprot IDs		Q96MA6	Q96Q83
PDB IDs			2IUW
Enriched GO Terms of Interacting Partners?		Histone H3-R2 Methylation Oxidative Single-stranded DNA Demethylation	Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Positive Regulation Of Neutrophil Differentiation Nuclear Speck Organization Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleus Organization Regulation Of Viral Process Positive Regulation Of NK T Cell Differentiation Positive Regulation Of Granulocyte Differentiation Sperm Chromatin Condensation Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Muscle Hypertrophy
Tagcloud ?			2og alkyl chromatin comprised demethylase dioxygenase display fe fto hits homologs hybrid interact marginally mediating modification oxoglutarate partners possess repairs rest reversal screens
Tagcloud (Difference) ?			2og alkyl chromatin comprised demethylase dioxygenase display fe fto hits homologs hybrid interact marginally mediating modification oxoglutarate partners possess repairs rest reversal screens
Tagcloud (Intersection) ?