AK8 and MAP3K7CL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AK8	MAP3K7CL
Gene Name		adenylate kinase 8	MAP3K7 C-terminal like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Nucleus Cytosol
	Molecular Function	Adenylate Kinase Activity Cytidylate Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding	Protein Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation Nucleoside Triphosphate Biosynthetic Process Ventricular System Development
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		10 interactors: ALKBH3 CCDC102B HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 RBM39 UBE2Z ZMAT2	6 interactors: AK8 CISH GPS2 KRT31 REL TAB3
Entrez ID		158067	56911
HPRD ID		12991	10764
Ensembl ID		ENSG00000165695	ENSG00000156265
Uniprot IDs		Q96MA6	B0EVZ6 B0EVZ8 P57077
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3-R2 Methylation Oxidative Single-stranded DNA Demethylation	I-kappaB Kinase/NF-kappaB Signaling JNK Cascade Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Protein Kinase Activity MAPK Cascade Negative Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Signal Transduction Negative Regulation Of Transferase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Signaling Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Intracellular Signal Transduction JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Negative Regulation Of JAK-STAT Cascade Growth Hormone Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Growth Hormone Stimulus Negative Regulation Of JNK Cascade Phosphorylation Inactivation Of MAPK Activity Negative Regulation Of Stress-activated MAPK Cascade Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Nucleoside Diphosphate Phosphorylation Negative Regulation Of Insulin Receptor Signaling Pathway Response To Growth Hormone Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Interleukin-12 Production Ventricular System Development
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