PIGT and PIGK

Number of citations of the paper that reports this interaction (PubMedID 12582175)
0

Data Source:
HPRD (in vivo, in vitro)

		PIGT	PIGK
Description		phosphatidylinositol glycan anchor biosynthesis class T	phosphatidylinositol glycan anchor biosynthesis class K
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle GPI-anchor Transamidase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex
	Molecular Function	Protein Binding GPI Anchor Binding	GPI-anchor Transamidase Activity Protein Binding Peptidase Activity Transferase Activity GPI Anchor Binding
	Biological Process	GPI Anchor Biosynthetic Process Attachment Of GPI Anchor To Protein Neuron Differentiation Neuron Apoptotic Process GPI Anchored Protein Biosynthesis	GPI Anchor Biosynthetic Process Proteolysis Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis
Pathways		Attachment of GPI anchor to uPAR	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Malaria ( 31844061)	Chronotype ( 27494321 30696823) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		3 interacting genes: GPAA1 PIGK UPF3A	3 interacting genes: ALPP GPAA1 PIGT
Entrez ID		51604	10026
HPRD ID		15136	05474
Ensembl ID		ENSG00000124155	ENSG00000142892
Uniprot IDs		Q969N2	Q92643
PDB IDs		7W72 7WLD 8IMX 8IMY	7W72 7WLD 8IMX 8IMY
Enriched GO Terms of Interacting Partners?		GPI-anchor Transamidase Activity GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Attachment Of GPI Anchor To Protein GPI Anchor Binding GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process Glycerophospholipid Biosynthetic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Positive Regulation Of MRNA Cis Splicing, Via Spliceosome Protein Maturation Glycerolipid Metabolic Process Phospholipid Metabolic Process Protein Retention In ER Lumen Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maintenance Of Protein Localization In Endoplasmic Reticulum Carbohydrate Derivative Biosynthetic Process Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Lipid Biosynthetic Process Organophosphate Biosynthetic Process Exon-exon Junction Complex Telomeric DNA Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Carbohydrate Derivative Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maintenance Of Protein Localization In Organelle Positive Regulation Of RNA Splicing Organophosphate Metabolic Process Maintenance Of Protein Location In Cell Maintenance Of Protein Location Endoplasmic Reticulum Membrane Lipid Metabolic Process Maintenance Of Location In Cell Negative Regulation Of MRNA Catabolic Process Maintenance Of Location	GPI-anchor Transamidase Complex Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis GPI Anchor Binding GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process Glycerophospholipid Biosynthetic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process GPI-anchor Transamidase Activity Glycerophospholipid Metabolic Process Alkaline Phosphatase Activity Protein Maturation Glycerolipid Metabolic Process Phospholipid Metabolic Process Protein Retention In ER Lumen Maintenance Of Protein Localization In Endoplasmic Reticulum Carbohydrate Derivative Biosynthetic Process Lipid Biosynthetic Process Organophosphate Biosynthetic Process Carbohydrate Derivative Metabolic Process Maintenance Of Protein Localization In Organelle Organophosphate Metabolic Process Maintenance Of Protein Location In Cell Maintenance Of Protein Location Endoplasmic Reticulum Membrane Lipid Metabolic Process Maintenance Of Location In Cell Phosphatase Activity Maintenance Of Location Phosphate-containing Compound Metabolic Process Neuron Apoptotic Process Side Of Membrane Endoplasmic Reticulum
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