PIGT and GPAA1

Number of citations of the paper that reports this interaction (PMID 11483512)
19

Data Source:
HPRD (in vivo, in vitro)

		PIGT	GPAA1
Gene Name		phosphatidylinositol glycan anchor biosynthesis, class T	glycosylphosphatidylinositol anchor attachment 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Cytoplasmic Membrane-bounded Vesicle Integral Component Of Endoplasmic Reticulum Membrane GPI-anchor Transamidase Complex	Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding
	Biological Process	C-terminal Protein Lipidation Attachment Of GPI Anchor To Protein Neuron Differentiation Post-translational Protein Modification Cellular Protein Metabolic Process Neuron Apoptotic Process	Protein Complex Assembly C-terminal Protein Lipidation Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Post-translational protein modification Attachment of GPI anchor to uPAR Post-translational modification: synthesis of GPI-anchored proteins	Post-translational protein modification Attachment of GPI anchor to uPAR Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: GPAA1 PIGK UPF3A	7 interactors: EIF3E GRIK5 PIGK PIGT PIGU PIN1 PRR13
Entrez ID		51604	8733
HPRD ID		15136	04334
Ensembl ID		ENSG00000124155	ENSG00000197858
Uniprot IDs		B7Z1N3 Q969N2	O43292
PDB IDs
Enriched GO Terms of Interacting Partners?		Attachment Of GPI Anchor To Protein C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Protein Retention In ER Lumen Maintenance Of Protein Localization In Endoplasmic Reticulum Lipid Biosynthetic Process Cellular Lipid Metabolic Process Organophosphate Metabolic Process Lipid Metabolic Process Positive Regulation Of Translation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Transport	Attachment Of GPI Anchor To Protein C-terminal Protein Lipidation GPI Anchor Biosynthetic Process GPI Anchor Metabolic Process Glycolipid Biosynthetic Process Protein Lipidation Lipoprotein Biosynthetic Process Phosphatidylinositol Biosynthetic Process Glycolipid Metabolic Process Lipoprotein Metabolic Process Glycerophospholipid Biosynthetic Process Post-translational Protein Modification Phosphatidylinositol Metabolic Process Membrane Lipid Metabolic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Lipid Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Macromolecule Biosynthetic Process Cellular Lipid Metabolic Process Organophosphate Metabolic Process Protein Retention In ER Lumen Cellular Protein Metabolic Process Maintenance Of Protein Localization In Endoplasmic Reticulum Lipid Metabolic Process Biosynthetic Process Negative Regulation Of Translational Initiation Formation Of Translation Preinitiation Complex Cellular Protein Modification Process
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