REEP1 and STX7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		REEP1	STX7
Description		receptor accessory protein 1	syntaxin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Membrane Mitochondrial Membrane Endoplasmic Reticulum Tubular Network	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule Secretory Vesicle
	Molecular Function	Protein Binding Microtubule Binding Olfactory Receptor Binding	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Protein Insertion Into Membrane Endoplasmic Reticulum Tubular Network Organization	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle-mediated Transport Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane
Pathways		Expression and translocation of olfactory receptors
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS		Atrial fibrillation ( 29892015 30061737) Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)	A body shape index ( 34021172) Cutaneous leishmaniasis ( 32830257) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: CLDN10 CSRP1 STX7 TMEM100 TMEM42 TMEM97 UNC93B1	52 interacting genes: ANKS6 AQP6 ARL13B CERS4 CISD2 CREB3 CREB3L1 CYBRD1 EBP ELOVL5 ENTPD2 FAM174A FAM210B FKBP7 GJC3 HSD17B11 HSD17B13 JAGN1 LIME1 LMNA MAPK6 MFF MGST3 MRM1 MTUS1 NAPA REEP1 RETREG3 RIC3 SAR1A SLC10A1 SLC10A6 SLC18A1 SLC35D4 SNAP29 STX1A STX2 STX6 STX8 TM4SF19 TMEM205 TMEM267 TMEM80 TMPRSS2 TMX2 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B ZFYVE27
Entrez ID		65055	8417
HPRD ID		07810	04449
Ensembl ID		ENSG00000068615	ENSG00000079950
Uniprot IDs		A0A1C7CYY3 A0A2R8Y6K6 A0A8I5KRE1 A0A8I5QKJ2 Q9H902	O15400
PDB IDs
Enriched GO Terms of Interacting Partners?			Organelle Membrane Fusion Vesicle Fusion Membrane Fusion SNAP Receptor Activity Organelle Fusion SNARE Complex Organelle Localization By Membrane Tethering Membrane Membrane Docking Vesicle Organization Syntaxin Binding Vesicle Docking Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Binding Chloride Channel Inhibitor Activity Membrane Organization Establishment Of Protein Localization Protein Transport Autophagosome Maturation Intracellular Protein Transport CORVET Complex Organelle Localization Vesicle-mediated Transport Endomembrane System Lysosomal Membrane Intracellular Protein Localization Autophagy Protein Binding Protein-containing Complex Disassembly Vesicle Docking Involved In Exocytosis Establishment Of Localization In Cell Late Endosome Membrane HOPS Complex Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Organelle Organization Endosome To Lysosome Transport Steroid Dehydrogenase Activity Cellular Localization Endoplasmic Reticulum Tubular Network Organization Exocytosis Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Cytoplasmic Vesicle Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Positive Regulation Of Histamine Secretion By Mast Cell Vesicle Tethering Complex Recycling Endosome Presynaptic Active Zone Membrane
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