REEP1 and TMEM100

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		REEP1	TMEM100
Description		receptor accessory protein 1	transmembrane protein 100
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Membrane Mitochondrial Membrane Endoplasmic Reticulum Tubular Network	Cytoplasm Endoplasmic Reticulum Plasma Membrane Membrane Perikaryon Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Olfactory Receptor Binding	Protein Binding
	Biological Process	Protein Insertion Into Membrane Endoplasmic Reticulum Tubular Network Organization	Angiogenesis Vasculogenesis In Utero Embryonic Development Endocardial Cushion Development Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Notch Signaling Pathway Cell Differentiation BMP Signaling Pathway Positive Regulation Of Endothelial Cell Differentiation Regulation Of Calcium-mediated Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Sensory Perception Of Pain Arterial Endothelial Cell Differentiation Cellular Response To BMP Stimulus Positive Regulation Of Vasculogenesis
Pathways		Expression and translocation of olfactory receptors
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS		Atrial fibrillation ( 29892015 30061737) Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)	Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856) Height ( 22021425) Pulse pressure ( 30578418) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: CLDN10 CSRP1 STX7 TMEM100 TMEM42 TMEM97 UNC93B1	33 interacting genes: AQP6 CCDC57 CD33 CLDN7 COMT CREB3 EBP ERGIC3 F11R FAM209A FNDC9 GJA8 GPR152 HSD17B13 IFNGR1 JAGN1 LHFPL5 MEOX2 NUP93 REEP1 RETREG3 RMDN3 RNF19B SLC30A4 SLC35A5 STING1 STX1A TMEM130 TMEM167B TMEM52B TMEM79 TMEM80 VSIR
Entrez ID		65055	55273
HPRD ID		07810	07719
Ensembl ID		ENSG00000068615	ENSG00000166292
Uniprot IDs		A0A1C7CYY3 A0A2R8Y6K6 A0A8I5KRE1 A0A8I5QKJ2 Q9H902	Q9NV29
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane
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