EPS8L2 and RPL23

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EPS8L2	RPL23
Gene Name		EPS8-like 2	ribosomal protein L23
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Vesicle Ruffle Membrane Protein Complex Extracellular Vesicular Exosome	Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Rho Guanyl-nucleotide Exchange Factor Activity Rac Guanyl-nucleotide Exchange Factor Activity	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Rho Protein Signal Transduction Positive Regulation Of Rho GTPase Activity Positive Regulation Of Rac GTPase Activity Regulation Of Rho Protein Signal Transduction Positive Regulation Of Ruffle Assembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination Ribosomal Protein Import Into Nucleus SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APP PTK2 RPL23 SOS1	8 interactors: APP BCCIP CDC42 CLU DAPP1 EPS8L2 IPO5 RELA
Entrez ID		64787	9349
HPRD ID		10940	04716
Ensembl ID		ENSG00000177106
Uniprot IDs		B7ZKL3 Q9H6S3	P62829
PDB IDs		1WWU 1WXB	3J3B
Enriched GO Terms of Interacting Partners?		Platelet Activation Axon Guidance Blood Coagulation Hemostasis Axonogenesis Axon Development Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Body Fluid Levels Wound Healing Chemotaxis Regulation Of ERBB Signaling Pathway Regulation Of Synapse Structure Or Activity Neuron Projection Morphogenesis Cell Activation Response To Wounding Cell Morphogenesis Involved In Differentiation Innate Immune Response Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Apoptotic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Programmed Cell Death Synaptic Growth At Neuromuscular Junction Cell Death Cell Morphogenesis Death Negative Regulation Of Neuron Differentiation Neuron Differentiation Cell Projection Organization Collateral Sprouting In Absence Of Injury Locomotion Netrin-activated Signaling Pathway Immune Response Defense Response Fc Receptor Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Rho GTPase Activity Regulation Of Developmental Growth Negative Regulation Of Neurogenesis Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Synapse Assembly Movement Of Cell Or Subcellular Component Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Catalytic Activity	Regulation Of Catalytic Activity Cellular Response To Stimulus Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response Positive Regulation Of Cellular Component Biogenesis Response To Stimulus Regulation Of Protein Catabolic Process Positive Regulation Of Neuron Death Platelet Degranulation Regulation Of Protein Phosphorylation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Blood Coagulation Hemostasis Regulation Of ERBB Signaling Pathway Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Microglial Cell Proliferation Acetaldehyde Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Synapse Structure Or Activity Hair Follicle Development Positive Regulation Of Protein Metabolic Process Hair Cycle Process Immune Response Response To Amino Acid Hair Cycle Regulation Of Phosphorylation Defense Response Synaptic Growth At Neuromuscular Junction Positive Regulation Of Neurofibrillary Tangle Assembly Positive Regulation Of Schwann Cell Differentiation Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Cell Projection Assembly Regulation Of Body Fluid Levels Positive Regulation Of NF-kappaB Transcription Factor Activity Wound Healing Microtubule-based Transport Negative Regulation Of Protein Complex Assembly Regulation Of Phosphorus Metabolic Process Regulation Of Signal Transduction Regulation Of Protein Stability Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Catalytic Activity Positive Regulation Of Immune Response Submandibular Salivary Gland Formation Collateral Sprouting In Absence Of Injury Actin Filament Branching
Tagcloud ?		acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl20 rpl22 rpl33 rpoa rps11 rps12 rps18 rps3 rps8 secx ugg
Tagcloud (Difference) ?		acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine	apocytochrome infa l20 l22 l33 liverwort marchantia peta petb petd preprotein psbb psbe psbf psbh rpl14 rpl16 rpl20 rpl22 rpl33 rpoa rps11 rps12 rps18 rps3 rps8 secx ugg
Tagcloud (Intersection) ?