PDCD1LG2

Description		programmed cell death 1 ligand 2
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Membrane
	Molecular Function	Protein Binding
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Type II Interferon Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide
Pathways		Co-inhibition by PD-1 PD-L1(CD274) glycosylation and translocation to plasma membrane
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Serum alkaline phosphatase levels ( 33339817)
Novel Interacting Genes		1 novel interacting genes: EXOSC8
Interacting Genes		20 interacting genes: ATP6V0C ERMP1 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35H1 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97
Entrez ID		80380
HPRD ID		16147
Ensembl ID		ENSG00000197646
Uniprot IDs		Q9BQ51
PDB IDs		6UMT 8J3V
Enriched GO Terms of Interacting Partners?		Membrane Glutamine Transport L-glutamine Transmembrane Transporter Activity Amino Acid Transmembrane Transport Amino Acid Transport
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