SYCE3 and INPP1

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		SYCE3	INPP1
Gene Name		synaptonemal complex central element protein 3	inositol polyphosphate-1-phosphatase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Central Element Nucleus Chromosome	Cytosol
	Molecular Function		Inositol-1,4-bisphosphate 1-phosphatase Activity Metal Ion Binding Inositol-1,3,4-trisphosphate 1-phosphatase Activity
	Biological Process	Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Spermatogenesis Positive Regulation Of Apoptotic Process Cell Division	Phosphate-containing Compound Metabolic Process Signal Transduction Dephosphorylation Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation
Pathways			Synthesis of IP2, IP, and Ins in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: BLOC1S6 HAUS1 INPP1	11 interactors: BRCA1 C9orf16 DYNLL1 LDOC1 LIG1 MEOX2 NDC80 NECAB2 NR1D1 SYCE3 USHBP1
Entrez ID		644186	3628
HPRD ID			00923
Ensembl ID		ENSG00000217442	ENSG00000151689
Uniprot IDs		A1L190	P49441 Q6IBG4
PDB IDs
Enriched GO Terms of Interacting Partners?		Secretion Of Lysosomal Enzymes Synaptic Vesicle Docking Endosome To Melanosome Transport Pigment Granule Maturation Cellular Pigment Accumulation Positive Regulation Of Pigment Cell Differentiation Positive Regulation Of Developmental Pigmentation Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Regulation Of Developmental Pigmentation Positive Regulation Of Natural Killer Cell Activation Microtubule-based Process Anterograde Axon Cargo Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanocyte Differentiation Melanosome Localization Neuroepithelial Cell Differentiation Axon Cargo Transport Inositol Phosphate Metabolic Process Synaptic Vesicle Exocytosis Cellular Pigmentation Vesicle Docking Involved In Exocytosis Developmental Pigmentation Spindle Assembly Phosphatidylinositol Phosphorylation Vesicle Docking Lipid Phosphorylation Post-Golgi Vesicle-mediated Transport Membrane Docking Centrosome Organization Microtubule Organizing Center Organization Synaptic Vesicle Transport Neurotransmitter Secretion Pigmentation Protein Secretion Spindle Organization Membrane Fusion Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Regulation Of Neurotransmitter Levels	Cell Cycle Process Cell Cycle Chromosome Segregation DNA Recombination Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Bile Acid Biosynthetic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cell Division Circadian Temperature Homeostasis Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Type B Pancreatic Cell Proliferation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Lipid Biosynthetic Process Double-strand Break Repair Otolith Morphogenesis Attachment Of Mitotic Spindle Microtubules To Kinetochore Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Negative Regulation Of Receptor Biosynthetic Process Lagging Strand Elongation Somite Specification Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Microtubule-based Process Nucleobase-containing Compound Metabolic Process Intracellular Receptor Signaling Pathway Otolith Development Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter DNA Ligation Involved In DNA Repair Regulation Of Histone H3-K9 Acetylation Organelle Organization Cellular Nitrogen Compound Metabolic Process Attachment Of Spindle Microtubules To Kinetochore DNA Replication Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation DNA Ligation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process
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