ARAP3 and PARD6B

Number of citations of the paper that reports this interaction (PubMedID 17314030)
0

Data Source:
BioGRID (two hybrid)

		ARAP3	PARD6B
Description		ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	par-6 family cell polarity regulator beta
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytoskeleton Plasma Membrane Membrane Lamellipodium Cell Projection	Nucleus Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Membrane Apical Plasma Membrane Cell Junction Protein-containing Complex Apical Part Of Cell Extracellular Exosome Tight Junction Anchoring Junction PAR Polarity Complex
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Zinc Ion Binding Phosphatidylinositol-3,4-bisphosphate Binding Metal Ion Binding	Protein Binding
	Biological Process	Cytoskeleton Organization Signal Transduction Vesicle-mediated Transport Regulation Of Actin Cytoskeleton Organization	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC3 GTPase cycle	Tight junction interactions RHOV GTPase cycle
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Diffuse large B cell lymphoma ( 25261932) Fasting plasma glucose ( 32682390) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Household income ( 31844048) Lung cancer ( 28604730) Mean arterial pressure ( 27618448) Offspring birth weight ( 31043758)	Bipolar disorder ( 21771265)
Interacting Genes		11 interacting genes: ANKS1A ARHGEF6 CD2AP CLNK GGA3 INPPL1 PARD6B SAMHD1 SH3KBP1 SNCA TNKS2	34 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB OGT PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4
Entrez ID		64411	84612
HPRD ID		09441	18703
Ensembl ID		ENSG00000120318	ENSG00000124171
Uniprot IDs		Q05CH1 Q8WWN8 Q9H7C1	Q9BYG5
PDB IDs		2KG5 2LNW 5JCP 5JD0 7A9B 7YIR 7YIS
Enriched GO Terms of Interacting Partners?		Cell Death ERK1 And ERK2 Cascade Apoptotic Process SH3 Domain Binding Vesicle-mediated Transport Actin Filament Organization Establishment Of Organelle Localization Cell Projection Programmed Cell Death Regulation Of Immune System Process Supramolecular Fiber Organization MAPK Cascade Response To Desipramine Negative Regulation Of Norepinephrine Uptake Protein Complex Oligomerization Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Destabilization Protein-containing Complex Cell-cell Junction DGTPase Activity DGTP Binding Triphosphoric Monoester Hydrolase Activity Deoxynucleoside Triphosphate Hydrolase Activity Plasma Membrane Bounded Cell Projection Assembly Regulation Of Amide Metabolic Process Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Neuron Projection DATP Catabolic Process DGTP Catabolic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cell Projection Assembly Actin Binding Protein Tetramerization Cellular Component Assembly Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Secretion By Cell Anchoring Junction DGTP Metabolic Process Regulated Exocytosis Regulation Of Immune Response Endocytosis Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway	Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity PAR Polarity Complex Establishment Of Cell Polarity Bicellular Tight Junction Apical Junction Complex Tight Junction GBD Domain Binding Cytoplasm Diacylglycerol-dependent Serine/threonine Kinase Activity GTP-dependent Protein Binding Cytoskeleton Organization Intracellular Protein Localization Response To Insulin Cell-cell Junction Organization Protein Kinase Binding Cell Cortex Response To Peptide Hormone Supramolecular Fiber Organization Cellular Response To Insulin Stimulus Regulation Of Synaptic Plasticity Phosphoserine Residue Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Apical Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Identical Protein Binding Intracellular Signal Transduction Establishment Of Golgi Localization Negative Regulation Of Protein Localization To Nucleus Actin Filament Organization Thioesterase Binding Establishment Of Centrosome Localization Organelle Organization Schmidt-Lanterman Incisure Plasma Membrane Cell Junction Organization Asymmetric Cell Division Regulation Of Synapse Organization Regulation Of Protein Localization Golgi Localization Regulation Of Cell Communication Extracellular Exosome Regulation Of Signaling Regulation Of Protein Localization To Membrane Regulation Of Programmed Cell Death Cellular Response To Peptide Hormone Stimulus Regulation Of Insulin Receptor Signaling Pathway Regulation Of D-glucose Transmembrane Transport Cellular Localization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?