NOTO and BTF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NOTO	BTF3
Description		notochord homeobox	basic transcription factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Cytosol Nascent Polypeptide-associated Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding
	Biological Process	Heart Looping Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Central Nervous System Development Brain Development Embryonic Pattern Specification Dorsal/ventral Pattern Formation Neuron Differentiation Notochord Development Motile Cilium Assembly Regulation Of Cilium Assembly	In Utero Embryonic Development Protein Transport Negative Regulation Of Protein Localization To Endoplasmic Reticulum
Pathways		Formation of axial mesoderm
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435)	Eyebrow thickness ( 26926045) Monobrow thickness ( 26926045)
Interacting Genes		31 interacting genes: ANKRD11 APOBEC1 BAG3 BANP BTF3 CCDC120 CEP19 CHAF1A EIPR1 ETV3L FAM9B FOXD2 FOXH1 GLYCTK HNRNPK IP6K3 KRT34 KRTAP19-7 KRTAP5-6 KRTAP6-1 KRTAP6-3 LDLRAP1 LRP10 MAGED1 MEIS2 NKX2-4 PIH1D2 POU4F2 SBK3 TTC23 UBTFL1	12 interacting genes: APP CDC42 CEBPA CSNK2B IFTAP MED21 NMT2 NOTO POLR2B TXLNA TXLNB ZDHHC17
Entrez ID		344022	689
HPRD ID			03966
Ensembl ID		ENSG00000214513	ENSG00000145741
Uniprot IDs		A8MTQ0	P20290
PDB IDs			3LKX 3MCB 7QWQ 7QWR 9F1B 9F1C 9F1D 9FQ0
Enriched GO Terms of Interacting Partners?		Intermediate Filament Positive Regulation Of Low-density Lipoprotein Particle Clearance Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Low-density Lipoprotein Particle Clearance	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Response To Interleukin-1 Cell Projection Morphogenesis Growth Cone Lamellipodium Neuron Projection Organization Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Amylin Binding Neuron Projection Morphogenesis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Peptide Positive Regulation Of Intracellular Signal Transduction Response To Cytokine Lipoprotein Particle Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of G Protein-coupled Receptor Internalization Macrophage Differentiation Endothelin Receptor Signaling Pathway Involved In Heart Process GBD Domain Binding Storage Vacuole Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Regulation Of DNA-templated Transcription Initiation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Ribonucleoside Binding RNA-directed RNA Polymerase Activity RNA-templated Transcription DNA-directed RNA Polymerase Activity Prostaglandin-I Synthase Activity Glycylpeptide N-tetradecanoyltransferase Activity Protein Lipidation N-terminal Peptidyl-glycine N-myristoylation Peptidyl-lysine N6-myristoyltransferase Activity Positive Regulation Of Ribosome Biogenesis
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