MAGEF1 and MMS19

Number of citations of the paper that reports this interaction (PubMedID 29225034)
0

Data Source:
BioGRID (pull down, affinity chromatography technology)

		MAGEF1	MMS19
Description		MAGE family member F1	MMS19 cytosolic iron-sulfur assembly component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Transcription Factor TFIIH Holo Complex Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Membrane MMXD Complex Cytosolic [4Fe-4S] Assembly Targeting Complex
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding Enzyme Binding Signaling Receptor Complex Adaptor Activity Nuclear Estrogen Receptor Binding Protein-macromolecule Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Double-strand Break Repair Via Homologous Recombination	DNA Repair DNA Damage Response Chromosome Segregation Positive Regulation Of DNA-templated Transcription Protein Maturation
Pathways			Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 30361487) Nose size ( 27182965)	Early spontaneous preterm birth ( 31194736) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		6 interacting genes: MDFI MMS19 NSMCE1 PHF7 TRAIP TRIM27	9 interacting genes: ESR1 ESR2 GTF2H1 MAGEF1 MTNR1A NCOA3 RARA SUMO2 THRB
Entrez ID		64110	64210
HPRD ID		14348	17579
Ensembl ID		ENSG00000177383	ENSG00000155229
Uniprot IDs		Q9HAY2	Q96T76
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Activity Protein Sumoylation Ubiquitin-protein Transferase Activity Negative Regulation Of Type I Interferon Production DNA Repair Post-translational Protein Modification Zinc Ion Binding Regulation Of Type I Interferon Production Transferase Activity Protein Modification By Small Protein Conjugation DNA Metabolic Process DNA Damage Response Negative Regulation Of Osteoclast Proliferation Cytosolic [4Fe-4S] Assembly Targeting Complex MMXD Complex Phosphatidylinositol 3-kinase Inhibitor Activity Nucleus Protein-DNA Covalent Cross-linking Repair Nucleoplasm Smc5-Smc6 Complex Transcription Coactivator Activity Positive Regulation Of Actin Nucleation Transcription Factor TFIIH Holo Complex Dorsal/ventral Axis Specification Trophoblast Giant Cell Differentiation Negative Regulation Of Cytokine Production Negative Regulation Of Viral Transcription Negative Regulation Of Interferon-beta Production Chromatin Looping Suppression Of Viral Release By Host Arp2/3 Complex-mediated Actin Nucleation Regulation Of Viral Transcription SUMO Transferase Activity Retromer Complex	Hormone-mediated Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Nuclear Receptor Activity Intracellular Receptor Signaling Pathway Retinoic Acid Receptor Signaling Pathway Response To Estradiol Cellular Response To Estradiol Stimulus Nuclear Estrogen Receptor Activity Transcription Coactivator Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Nuclear Protein Quality Control By The Ubiquitin-proteasome System Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Estrogen Response Element Binding Regulation Of RNA Metabolic Process Cellular Response To Hormone Stimulus Enzyme Binding Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Estrogen Stimulus Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Sequence-specific DNA Binding Negative Regulation Of Transcription By RNA Polymerase II Nuclear Steroid Receptor Activity Cellular Response To Lipid Mating Behavior Estrogen Receptor Signaling Pathway Chromatin Binding Negative Regulation Of MiRNA Transcription Steroid Binding Nuclear Thyroid Hormone Receptor Binding Chromatin Reproductive Behavior Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Macromolecule Metabolic Process Response To Hormone Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity Regulation Of Macromolecule Biosynthetic Process MRNA Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process
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