MAGEF1 and NSMCE1

Number of citations of the paper that reports this interaction (PMID 20864041)
40

Data Source:
BioGRID (pull down)

		MAGEF1	NSMCE1
Gene Name		melanoma antigen family F, 1	non-SMC element 1 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Chromosome, Telomeric Region Nucleoplasm Cytoplasm Smc5-Smc6 Complex Intracellular Membrane-bounded Organelle
	Molecular Function		Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process		DNA Repair DNA Recombination Protein Ubiquitination Intracellular Signal Transduction Positive Regulation Of Response To DNA Damage Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: MDFI NSMCE1 TRIM27	2 interactors: MAGEF1 UBE2D2
Entrez ID		64110	197370
HPRD ID		14348	17648
Ensembl ID		ENSG00000177383	ENSG00000169189
Uniprot IDs		Q9HAY2	Q8WV22
PDB IDs			2CT0 3NW0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Transport Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Calcium Ion Import Negative Regulation Of Transport Interferon-gamma Secretion Protein Ubiquitination Negative Regulation Of Viral Release From Host Cell Protein Modification By Small Protein Conjugation Regulation Of Protein Transport Trophoblast Giant Cell Differentiation Regulation Of Establishment Of Protein Localization Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Protein Kinase Activity Regulation Of Calcium Ion Import Cytoplasmic Sequestering Of Protein Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Kinase Activity Regulation Of Protein Localization Cell Differentiation Involved In Embryonic Placenta Development Protein K63-linked Ubiquitination Cytokine Secretion Protein Trimerization Activation Of JUN Kinase Activity Negative Regulation Of Cytokine Secretion Negative Regulation Of Adaptive Immune Response Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Negative Regulation Of Calcium Ion Transport Negative Regulation Of DNA Binding Arp2/3 Complex-mediated Actin Nucleation Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transmembrane Transport Single Organism Reproductive Process Actin Nucleation Retrograde Transport, Endosome To Golgi Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of JUN Kinase Activity Regulation Of Phosphorylation	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K48-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Protein Polyubiquitination Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Response To Hypoxia
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