MMS19

Description		MMS19 cytosolic iron-sulfur assembly component
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIIH Holo Complex Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Membrane MMXD Complex Cytosolic [4Fe-4S] Assembly Targeting Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Enzyme Binding Signaling Receptor Complex Adaptor Activity Nuclear Estrogen Receptor Binding Protein-macromolecule Adaptor Activity
	Biological Process	DNA Repair DNA Damage Response Chromosome Segregation Positive Regulation Of DNA-templated Transcription Protein Maturation
Pathways		Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS		Early spontaneous preterm birth ( 31194736) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		9 interacting genes: ESR1 ESR2 GTF2H1 MAGEF1 MTNR1A NCOA3 RARA SUMO2 THRB
Entrez ID		64210
HPRD ID		17579
Ensembl ID		ENSG00000155229
Uniprot IDs		Q96T76
PDB IDs
Enriched GO Terms of Interacting Partners?		Hormone-mediated Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Nuclear Receptor Activity Intracellular Receptor Signaling Pathway Retinoic Acid Receptor Signaling Pathway Response To Estradiol Cellular Response To Estradiol Stimulus Nuclear Estrogen Receptor Activity Transcription Coactivator Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Nuclear Protein Quality Control By The Ubiquitin-proteasome System Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Estrogen Response Element Binding Regulation Of RNA Metabolic Process Cellular Response To Hormone Stimulus Enzyme Binding Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Estrogen Stimulus Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Sequence-specific DNA Binding Negative Regulation Of Transcription By RNA Polymerase II Nuclear Steroid Receptor Activity Cellular Response To Lipid Mating Behavior Estrogen Receptor Signaling Pathway Chromatin Binding Negative Regulation Of MiRNA Transcription Steroid Binding Nuclear Thyroid Hormone Receptor Binding Chromatin Reproductive Behavior Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Macromolecule Metabolic Process Response To Hormone Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity Regulation Of Macromolecule Biosynthetic Process MRNA Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process
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