CENPK and PCBD2

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		CENPK	PCBD2
Gene Name		centromere protein K	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Nucleoplasm Cytosol	Cellular_component Nucleus Mitochondrion
	Molecular Function		Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
	Biological Process	Mitotic Cell Cycle Nucleosome Assembly CENP-A Containing Nucleosome Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter	Tetrahydrobiopterin Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Protein Homotetramerization Protein Heterooligomerization Oxidation-reduction Process
Pathways		Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 18391951)
Protein-Protein Interactions		5 interactors: AP1G2 CENPH MRFAP1L1 PCBD2 SOX6	31 interactors: AATF APP ASCC2 BRF1 C1D CDC5L CENPK CHAF1A GTF2E1 HES4 IRF2BP1 KCNIP3 MAGEA11 MED21 MED30 MED4 MED7 MET PBXIP1 PCBD1 PHF14 PML RUNX1T1 SNW1 SSX3 SSX5 STAT3 TAL2 TGIF2LY XBP1 ZZZ3
Entrez ID		64105	84105
HPRD ID		13323	17824
Ensembl ID		ENSG00000123219
Uniprot IDs		Q9BS16	Q9H0N5
PDB IDs			4C45
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mesenchymal Stem Cell Differentiation Regulation Of Mesenchymal Stem Cell Differentiation Oligodendrocyte Cell Fate Specification Tetrahydrobiopterin Biosynthetic Process	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Apoptotic Process Negative Regulation Of Gene Expression Programmed Cell Death Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Cell Death Death Stem Cell Maintenance Transcription From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Histone Modification Negative Regulation Of Cell Differentiation Stem Cell Development Developmental Process Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation
Tagcloud ?		anaemia anaemic appearing cdca8 cdkn2d characterise claudin claudins cldn13 cldn4 congolense e2f2 enucleation erythroblast erythropoiesis erythropoietic gypa haematopoietic neighbour ordinately partitioning phylogenetically polarisation rhd tight tmcc2 trim10 trypanosoma unreported
Tagcloud (Difference) ?		anaemia anaemic appearing cdca8 cdkn2d characterise claudin claudins cldn13 cldn4 congolense e2f2 enucleation erythroblast erythropoiesis erythropoietic gypa haematopoietic neighbour ordinately partitioning phylogenetically polarisation rhd tight tmcc2 trim10 trypanosoma unreported
Tagcloud (Intersection) ?