AP1B1 and SLC2A8

Number of citations of the paper that reports this interaction (PubMedID 16723738)
0

Data Source:
BioGRID (pull down)

		AP1B1	SLC2A8
Description		adaptor related protein complex 1 subunit beta 1	solute carrier family 2 member 8
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Early Endosome Golgi Apparatus Cytosol Synaptic Vesicle Endomembrane System Membrane Membrane Coat AP-1 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane	Lysosomal Membrane Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding	Fructose Transmembrane Transporter Activity D-glucose Binding Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity
	Biological Process	Kidney Development Intracellular Protein Transport Determination Of Left/right Symmetry Heart Development Protein Transport Vesicle-mediated Transport Platelet Dense Granule Organization Basolateral Protein Secretion Melanosome Assembly	Response To Hypoxia Carbohydrate Metabolic Process Male Meiosis I Insulin Receptor Signaling Pathway Hexose Transmembrane Transport Fructose Transmembrane Transport Transmembrane Transport Dehydroascorbic Acid Transport D-glucose Transmembrane Transport
Pathways		Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis	Cellular hexose transport Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Carotid atherosclerosis in HIV infection ( 20009918) Haemorrhoidal disease ( 33888516) Heel bone mineral density ( 28869591 30598549) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Pancreatic cancer ( 25086665) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Bipolar disorder ( 20351715) Major depressive disorder ( 27777418) Metabolite levels (HVA) ( 23319000)
Interacting Genes		45 interacting genes: - AGR3 AP1G1 AP1M2 ARF1 ARF5 ARF6 ARRB2 ATF7IP ATM ATR BARD1 BUB1 BUB1B CEBPA CLTC CREBBP CRYBB1 FARS2 FILNC1 FMNL2 FNDC11 GPANK1 GTF2I KIF13A LDLRAP1 MLH1 MSGN1 MTNR1B MYG1 NECAP1 NTRK2 NUP54 PIP5K1C PLK2 POM121 PRKDC PSORS1C2 RNF39 SHBG SLC2A8 SMAD2 TBC1D22B TSGA10IP U2AF1	4 interacting genes: AP1B1 AP2A2 AP2B1 BDKRB2
Entrez ID		162	29988
HPRD ID		02541	05580
Ensembl ID		ENSG00000100280	ENSG00000136856
Uniprot IDs		Q10567	A0A087WT42 Q5VVV9 Q8WZ05 Q9NY64
PDB IDs		4HMY 4P6Z 6CM9 6CRI 6D83 6D84 6DFF 7R4H 7UX3 8D4C 8D4D 8D4E 8D4F 8D4G 8D9R 8D9S 8D9T 8D9U 8D9V 8D9W
Enriched GO Terms of Interacting Partners?		Histone H2AXS139 Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Process Presynaptic Endocytosis Establishment Of RNA Localization To Telomere Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Telomerase Catalytic Core Complex Assembly Negative Regulation Of Cell Cycle Regulation Of Cellular Response To Heat Intracellular Protein Localization Regulation Of Cell Cycle Clathrin Adaptor Activity Negative Regulation Of Cell Cycle Process Establishment Of Protein Localization DNA-dependent Protein Kinase Activity Intracellular Protein Transport Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Cell Cycle Phase Transition Clathrin-coated Pit Protein Transport Basolateral Protein Secretion Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Mitotic Cell Cycle Clathrin-coated Vesicle Membrane Vesicle-mediated Transport In Synapse MutSalpha Complex Binding Homologous Recombination Synaptic Vesicle Endocytosis Negative Regulation Of Mitotic Nuclear Division Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Telomere Localization Protein Localization To Chromosome Somatic Cell DNA Recombination Trans-Golgi Network Membrane Endocytosis Somitogenesis Meiotic Sister Chromatid Cohesion Male Meiotic Nuclear Division Nucleotide Binding Regulation Of Receptor-mediated Endocytosis Segmentation Response To Gamma Radiation Mitotic G2/M Transition Checkpoint	Clathrin Adaptor Complex Membrane Coat Postsynaptic Neurotransmitter Receptor Internalization AP-2 Adaptor Complex Clathrin Adaptor Activity Endolysosome Membrane Clathrin-coated Endocytic Vesicle Clathrin-dependent Endocytosis Clathrin Binding Synaptic Vesicle Endocytosis Presynaptic Endocytosis Clathrin-coated Endocytic Vesicle Membrane Receptor Internalization Clathrin-coated Pit Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Secretion Endocytic Vesicle Membrane Intracellular Protein Transport Vesicle-mediated Transport In Synapse Cytoplasmic Side Of Plasma Membrane Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Synaptic Vesicle Cytoplasmic Vesicle Bradykinin Receptor Activity Kidney Development Receptor-mediated Endocytosis Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator Protein Transport Signal Sequence Binding Vesicle-mediated Transport Basolateral Protein Secretion Extrinsic Component Of Presynaptic Endocytic Zone Membrane Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Type 1 Angiotensin Receptor Binding Intracellular Transport Endomembrane System Clathrin Coat Heart Development Establishment Of Protein Localization Postsynaptic Endocytic Zone Cellular Localization Establishment Of Localization In Cell Lysosomal Membrane AP-1 Adaptor Complex Secretion By Cell Regulation Of Cellular Response To Osmotic Stress Regulation Of Response To Osmotic Stress Endocytosis
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