ZC3H10 and RBM38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZC3H10	RBM38
Description		zinc finger CCCH-type containing 10	RNA binding motif protein 38
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	Post-transcriptional Regulation Of Gene Expression Regulation Of RNA Splicing Negative Regulation Of MiRNA Processing	MRNA Processing Negative Regulation Of Cell Population Proliferation RNA Splicing Regulation Of Myotube Differentiation Cell Differentiation DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of RNA Splicing Regulation Of Cell Cycle 3'-UTR-mediated MRNA Stabilization
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glycated hemoglobin levels ( 34059833) Haemorrhoidal disease ( 33888516) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 29403010 28017375) Mean corpuscular volume ( 28017375 28453575 20139978 29403010) Mean platelet volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Neutrophil count ( 32888494) Red blood cell traits ( 23222517) Response to statin therapy ( 20339536) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Type 2 diabetes ( 23300278)
Interacting Genes		52 interacting genes: ACTMAP ALG13 AOC1 APPBP2 ARID5A ATXN1 BOLL C10orf55 CRX DAB1 DAZAP2 DMRTB1 ESRP1 FAM168B FOSB FOXH1 HIVEP1 INTS11 KLHDC7B KRTAP19-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MIR143 MSX2 NCS1 NFYA OTX2 OXER1 PIAS2 PICALM PLA2G10 POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBFOX2 RBM38 RBPMS RBPMS2 RNF4 SNRPA SPMIP9 STAM2 TENT5A TENT5B UBE2I ZNF34	4 interacting genes: HNRNPH1 MDM2 RCHY1 ZC3H10
Entrez ID		84872	55544
HPRD ID		07860	15268
Ensembl ID		ENSG00000135482	ENSG00000132819
Uniprot IDs		Q96K80	Q9H0Z9
PDB IDs			2CQD 6JVX 6JVY
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Stabilization Negative Regulation Of RNA Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process MRNA 3'-UTR Binding Regulation Of RNA Stability Regulation Of Primary Metabolic Process MRNA Binding Cytoplasmic Stress Granule Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process DNA Binding Negative Regulation Of Macromolecule Metabolic Process Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome Poly(A) RNA Polymerase Activity Positive Regulation Of Biosynthetic Process Regulation Of MRNA Processing Positive Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of DNA-templated Transcription Intermediate Filament Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process RNA Binding Transcription Factor Binding SUMO Transferase Activity 3'-UTR-mediated MRNA Stabilization	Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process P53 Binding Response To Formaldehyde Protein Autoubiquitination Ubiquitin Binding Cellular Response To Vitamin B1 Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of RNA Splicing Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Vitamin B1 NEDD8 Ligase Activity Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Actinomycin D Regulation Of Ubiquitin-dependent Protein Catabolic Process Response To Water-immersion Restraint Stress Traversing Start Control Point Of Mitotic Cell Cycle Cellular Response To Actinomycin D Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Cellular Response To UV-C Error-free Translesion Synthesis Receptor Serine/threonine Kinase Binding Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Ubiquitin-protein Transferase Activity Negative Regulation Of MiRNA Processing Atrial Septum Development Fibroblast Activation Peroxisome Proliferator Activated Receptor Binding Cellular Response To Antibiotic 5S RRNA Binding Regulation Of Proteolysis Regulation Of Protein Catabolic Process Ubiquitin Protein Ligase Activity Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Response To UV-C Negative Regulation Of MiRNA-mediated Gene Silencing Negative Regulation Of Post-transcriptional Gene Silencing By Regulatory NcRNA Regulation Of MiRNA Processing Regulation Of Regulatory NcRNA Processing Cellular Response To Estrogen Stimulus Response To Magnesium Ion RNA Binding Poly(U) RNA Binding Nucleus SUMO Transferase Activity Endocardial Cushion Morphogenesis Response To Ether
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