SLC9A4

Description		solute carrier family 9 member A4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Zymogen Granule Membrane
	Molecular Function	Antiporter Activity Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity
	Biological Process	Gastric Acid Secretion Glandular Epithelial Cell Development Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transport Regulation Of PH Regulation Of Intracellular PH Transmembrane Transport Transepithelial Ammonium Transport Potassium Ion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport
Pathways		Sodium/Proton exchangers
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Appendicular lean mass ( 33097823) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Basophil count ( 32888494) Bisphosphonate-associated atypical femoral fracture ( 31006051) Celiac disease ( 25920553 30572963 18311140) Crohn's disease ( 28067908) Delirium ( 29631748) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Lymphocyte count ( 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Night sleep phenotypes ( 27126917) Serum protein levels (sST2) ( 23999434) White blood cell types ( 21738478)
Interacting Genes		2 interacting genes: CHP1 CHP2
Entrez ID		389015
HPRD ID		15973
Ensembl ID		ENSG00000180251
Uniprot IDs		Q6AI14
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphatase Activity Regulation Of Dephosphorylation Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Protein Import Into Nucleus Regulation Of Calcium-mediated Signaling Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Protein Transport Regulation Of Protein Localization To Nucleus Positive Regulation Of Protein Transport Regulation Of Intracellular Transport Negative Regulation Of Phosphatase Activity Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Protein Glycosylation Transporter Complex Positive Regulation Of Phosphatase Activity Positive Regulation Of Protein Localization Negative Regulation Of Dephosphorylation Regulation Of Protein Transport Positive Regulation Of Dephosphorylation Regulation Of Protein Glycosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Calcium Ion Binding Positive Regulation Of Phospholipid Biosynthetic Process Sodium:proton Antiporter Activity Regulation Of Protein Autophosphorylation Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Phospholipid Biosynthetic Process Cellular Response To Acidic PH Negative Regulation Of Protein Import Into Nucleus Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Transport Negative Regulation Of Calcium-mediated Signaling Regulation Of Protein Localization Response To Acidic PH Positive Regulation Of Protein Targeting To Membrane Cellular Response To PH Regulation Of Protein Targeting To Membrane Positive Regulation Of Sodium Ion Transport Protein Export From Nucleus
Tagcloud ?