CXCL5 and CXCL3

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CXCL5	CXCL3
Description		C-X-C motif chemokine ligand 5	C-X-C motif chemokine ligand 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Identical Protein Binding CXCR Chemokine Receptor Binding	Cytokine Activity Chemokine Activity
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Killing Of Cells Of Another Organism Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		CXCL5 levels ( 25147954) Inflammatory bowel disease ( 23128233) Metabolite levels ( 22916037) Urate levels (BMI interaction) ( 25811787)	Inflammatory bowel disease ( 23128233) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		20 interacting genes: ACKR1 ACTN3 ALPP CCL11 CCL20 CXCL1 CXCL14 CXCL2 CXCL3 CXCR1 CXCR2 EFEMP2 FBLN1 GRN MEOX2 MGAT5B MMP9 NOTCH2NLA VWC2L XCL2	6 interacting genes: CCL11 CXCL5 CXCL6 CXCR1 CXCR2 XCL2
Entrez ID		6374	2921
HPRD ID		08976	00742
Ensembl ID		ENSG00000163735	ENSG00000163734
Uniprot IDs		P42830 Q6I9S7	P19876
PDB IDs		2MGS 8XWS 8XX7	8XWF 8XX3
Enriched GO Terms of Interacting Partners?		Chemokine Activity Cell Chemotaxis Cytokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Locomotion Antimicrobial Humoral Response Killing Of Cells Of Another Organism Humoral Immune Response Cell Migration Chemokine-mediated Signaling Pathway Extracellular Region Cell Killing Cell Motility Inflammatory Response Extracellular Space Interleukin-8-mediated Signaling Pathway Interleukin-8 Receptor Activity Granulocyte Chemotaxis C-C Chemokine Binding Immune Response Granulocyte Migration Interleukin-8 Binding Leukocyte Migration Defense Response Elastic Fiber Defense Response To Symbiont Myeloid Leukocyte Migration Immune System Process Defense Response To Other Organism Embryo Implantation Leukocyte Chemotaxis Signal Transduction Positive Regulation Of Cell Migration Neutrophil Chemotaxis C-X-C Chemokine Receptor Activity Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Neutrophil Migration Response To External Biotic Stimulus Regulation Of Cell Migration Cytokine-mediated Signaling Pathway Regulation Of Cell Motility Regulation Of Locomotion Response To Other Organism Dendritic Cell Chemotaxis G Protein-coupled Receptor Signaling Pathway Mononuclear Cell Migration Chemokine Receptor Activity C-C Chemokine Receptor Activity	Cell Chemotaxis Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Granulocyte Migration Chemotaxis Locomotion Myeloid Leukocyte Migration Leukocyte Chemotaxis Chemokine Activity Neutrophil Chemotaxis Leukocyte Migration Neutrophil Migration Cell Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cytokine-mediated Signaling Pathway Cell Motility Interleukin-8-mediated Signaling Pathway Immune Response Interleukin-8 Receptor Activity Antimicrobial Humoral Response Inflammatory Response Interleukin-8 Binding Cytokine Activity Humoral Immune Response G Protein-coupled Receptor Signaling Pathway Immune System Process C-X-C Chemokine Receptor Activity CXCR Chemokine Receptor Binding Dendritic Cell Chemotaxis Defense Response Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Dendritic Cell Migration CCR Chemokine Receptor Binding Neutrophil Activation Defense Response To Symbiont Defense Response To Other Organism Cell Surface Receptor Signaling Pathway Signal Transduction Response To Other Organism Receptor Internalization Response To External Biotic Stimulus Secretory Granule Membrane Mononuclear Cell Migration Extracellular Space Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Myeloid Leukocyte Activation Response To Stress Mammary Duct Terminal End Bud Growth
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