MX1 and TRPC7

Number of citations of the paper that reports this interaction (PMID 15757897)
7

Data Source:
HPRD (in vitro, in vivo)

		MX1	TRPC7
Gene Name		MX dynamin-like GTPase 1	transient receptor potential cation channel, subfamily C, member 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Nuclear Membrane Perinuclear Region Of Cytoplasm	Nuclear Envelope Cis-Golgi Network Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Calcium Channel Activity Protein Binding
	Biological Process	Apoptotic Process Defense Response Signal Transduction Metabolic Process Response To Virus Cytokine-mediated Signaling Pathway Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Type I Interferon Signaling Pathway	Manganese Ion Transport Axon Guidance Blood Coagulation Platelet Activation Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling Antiviral mechanism by IFN-stimulated genes	G alpha (q) signalling events Signaling by GPCR Axon guidance TRP channels Effects of PIP2 hydrolysis Platelet calcium homeostasis G alpha (q) signalling events GPCR downstream signaling Ion channel transport Platelet homeostasis Role of second messengers in netrin-1 signaling Gastrin-CREB signalling pathway via PKC and MAPK Elevation of cytosolic Ca2+ levels Stimuli-sensing channels Platelet activation, signaling and aggregation Netrin-1 signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ACTB APP BLM CAB39L DAXX FANCA PIAS1 SIAH1 SP100 SUMO1 TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBB	4 interactors: ITPR3 MX1 TRPC3 TRPC6
Entrez ID		4599	57113
HPRD ID		00919	18228
Ensembl ID		ENSG00000157601	ENSG00000069018
Uniprot IDs		P20591	Q9HCX4
PDB IDs		3LJB 3SZR 3ZYS
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Calcium Ion Transmembrane Transport Neuron Development Cell Morphogenesis Movement Of Cell Or Subcellular Component Response To Stimulus Neuron Differentiation Cell Projection Organization Calcium Ion Transport Locomotion Platelet Activation Response To Stress Generation Of Neurons Neurogenesis Cell Development Response To External Stimulus Regulation Of Body Fluid Levels Cell Activation Nervous System Development Blood Coagulation Hemostasis Intracellular Receptor Signaling Pathway Anatomical Structure Development Anatomical Structure Morphogenesis Innate Immune Response Metal Ion Transport System Development Cell Differentiation Cation Transmembrane Transport Regulation Of Binding Positive Regulation Of Calcium Ion Transport Developmental Process Wound Healing Multicellular Organismal Development Interferon-gamma-mediated Signaling Pathway Response To Wounding Cation Transport Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Cellular Response To Interferon-gamma Protein Sumoylation	Platelet Activation Calcium Ion Transmembrane Transport Calcium Ion Transport Blood Coagulation Hemostasis Response To Inorganic Substance Regulation Of Body Fluid Levels Wound Healing Positive Regulation Of Calcium Ion Transport Cell Activation Response To Wounding Response To Calcium Ion Metal Ion Transport Cation Transmembrane Transport Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Regulation Of Calcium Ion Transport Positive Regulation Of Ion Transport Response To Stress Cation Transport Ion Transmembrane Transport Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Cellular Calcium Ion Homeostasis Sensory Perception Of Sweet Taste Calcium Ion Homeostasis Sensory Perception Of Umami Taste Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Response To Metal Ion Transmembrane Transport Axon Guidance Ion Transport Response To External Stimulus Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Axonogenesis Inositol Phosphate-mediated Signaling Positive Regulation Of Cardiac Muscle Hypertrophy Cellular Chemical Homeostasis Ion Homeostasis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Regulation Of Ion Transport Neuron Projection Morphogenesis Response To ATP Response To Organic Substance Cellular Homeostasis Regulation Of Cardiac Muscle Hypertrophy
Tagcloud ?		antiproliferative apl appear autoantigen bodies contain disruption elucidation fusion harbors ifn ifns inactivation interferons labelled leukemogenesis link mediate mediator microspeckles nbs ndp52 pml promyelocytic rxrs sequestration sp100 speckles suppressing	21q22 affective bipolar c05c12 caenorhabditis caudate cdna consists constitute d21s171 d21s400 deafness elegans exons f54d1 hereditary holoprosencephaly hypothetical kb knobloch libraries mapped mentioned nonsyndromic northern noti spanning t01h8
Tagcloud (Difference) ?		antiproliferative apl appear autoantigen bodies contain disruption elucidation fusion harbors ifn ifns inactivation interferons labelled leukemogenesis link mediate mediator microspeckles nbs ndp52 pml promyelocytic rxrs sequestration sp100 speckles suppressing	21q22 affective bipolar c05c12 caenorhabditis caudate cdna consists constitute d21s171 d21s400 deafness elegans exons f54d1 hereditary holoprosencephaly hypothetical kb knobloch libraries mapped mentioned nonsyndromic northern noti spanning t01h8
Tagcloud (Intersection) ?