MX1 and PSG9

		MX1	PSG9
Description		MX dynamin like GTPase 1	pregnancy specific beta-1-glycoprotein 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Microtubule Plasma Membrane Membrane Nuclear Membrane Synapse Perinuclear Region Of Cytoplasm Presynapse	Extracellular Region Transforming Growth Factor Beta Ligand-receptor Complex
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Identical Protein Binding	Protein-containing Complex Binding
	Biological Process	Immune System Process Apoptotic Process Defense Response Signal Transduction Response To Virus Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Response To Type I Interferon Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Interleukin-27-mediated Signaling Pathway Antiviral Innate Immune Response	Tolerance Induction Dependent Upon Immune Response Fc Receptor Mediated Inhibitory Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Female Pregnancy Regulation Of Regulatory T Cell Differentiation Positive Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		42 interacting genes: ACTB ADRM1 APP BLM BRD7 C7orf25 CAB39L CASP8AP2 CBX4 CHD3 DAXX EPM2AIP1 FANCA FXR1 GMEB1 HMGXB4 KIF26B KLHL35 LRRC4B MCCD1 PIAS1 PIAS2 PLRG1 PSD3 RELA SIAH1 SIRPA SLC25A3 SP100 TDG TRPC1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TUBA1A TUBB ZBTB16 ZCCHC12 ZNF251 ZNF623	5 interacting genes: EEF1A1 LRIF1 PTPN12 SMAD2 SMAD4
Entrez ID		4599	5678
HPRD ID		00919	08897
Ensembl ID		ENSG00000157601	ENSG00000183668
Uniprot IDs		H9KVC7 P20591	B4DTI5 E7EW65 G3XAA7 M0R0U8 Q00887 Q05DN5
PDB IDs		3LJB 3SZR 3ZYS 4P4S 4P4T 4P4U 5GTM
Enriched GO Terms of Interacting Partners?		Store-operated Calcium Channel Activity Inositol 1,4,5 Trisphosphate Binding Cation Channel Complex PML Body Regulation Of Cytosolic Calcium Ion Concentration Calcium Channel Activity Transcription Corepressor Activity Cytoplasmic Ribonucleoprotein Granule SUMO Ligase Activity Actinin Binding Negative Regulation Of Cytokine Production Involved In Inflammatory Response Monoatomic Ion Channel Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Intracellular Calcium Ion Homeostasis SUMO Transferase Activity Calcium Ion Transmembrane Transport Calcium Ion Homeostasis Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Positive Regulation Of Cell-cell Adhesion Negative Regulation Of RNA Metabolic Process Calcium Ion Transport Regulation Of Cytokine Production Involved In Inflammatory Response Nucleus Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Cell Development Regulation Of T Cell Activation Identical Protein Binding Regulation Of T Cell Differentiation Intracellular Monoatomic Cation Homeostasis Associative Learning Inorganic Ion Homeostasis Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Macromolecule Biosynthetic Process Protein Homodimerization Activity Intracellular Monoatomic Ion Homeostasis Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Cell Differentiation Regulation Of Synapse Organization Ubiquitin Protein Ligase Binding Regulation Of Multicellular Organismal Development Positive Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Nuclear Envelope Lumen SUMO Binding Synapse Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing	Activin Responsive Factor Complex Response To Growth Factor Heteromeric SMAD Protein Complex SMAD Protein Complex Secondary Palate Development I-SMAD Binding SMAD Protein Signal Transduction R-SMAD Binding Activin Receptor Signaling Pathway Embryonic Axis Specification Endoderm Development Cellular Response To Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus Gastrulation SMAD Binding Response To Epidermal Growth Factor Mesoderm Development Embryonic Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Developmental Growth Roof Of Mouth Development Response To Transforming Growth Factor Beta Axis Specification Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Homomeric SMAD Protein Complex Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Susceptibility To T Cell Mediated Cytotoxicity Regulation Of Epithelial To Mesenchymal Transition Zygotic Specification Of Dorsal/ventral Axis Response To Glucose Ameboidal-type Cell Migration Paraxial Mesoderm Morphogenesis Left Ventricular Cardiac Muscle Tissue Morphogenesis Metanephric Mesenchyme Morphogenesis Susceptibility To Natural Killer Cell Mediated Cytotoxicity Response To Monosaccharide Eukaryotic Translation Elongation Factor 1 Complex Positive Regulation Of Luteinizing Hormone Secretion Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Carbohydrate Anterior/posterior Pattern Specification Mesoderm Morphogenesis Sulfate Binding Endocardial Cell Differentiation
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