SLC30A2 and TNFRSF12A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SLC30A2	TNFRSF12A
Gene Name		solute carrier family 30 (zinc transporter), member 2	tumor necrosis factor receptor superfamily, member 12A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Late Endosome Integral Component Of Membrane	Ruffle Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Cation Transmembrane Transporter Activity	Protein Binding
	Biological Process	Zinc Ion Transport Transmembrane Transport Positive Regulation Of Sequestering Of Zinc Ion Cation Transmembrane Transport	Angiogenesis Substrate-dependent Cell Migration, Cell Attachment To Substrate Positive Regulation Of Apoptotic Process Regulation Of Angiogenesis Positive Regulation Of Axon Extension Regulation Of Wound Healing Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Metal ion SLC transporters Zinc efflux and compartmentalization by the SLC30 family Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Zinc transporters SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ADAM33 CCDC155 CCL4 CCL4L2 PVR TNFRSF12A	9 interactors: PVR PVRL2 RAC1 SLC30A2 TNFSF12 TRAF1 TRAF2 TRAF3 TRAF5
Entrez ID		7780	51330
HPRD ID		18057	05801
Ensembl ID		ENSG00000158014	ENSG00000006327
Uniprot IDs		B3KSN7 Q9BRI3	Q9NP84
PDB IDs			2EQP 2KMZ 2RPJ
Enriched GO Terms of Interacting Partners?		Cell Migration Cell Motility Locomotion Movement Of Cell Or Subcellular Component Chromosome Localization To Nuclear Envelope Involved In Synapsis Susceptibility To T Cell Mediated Cytotoxicity Substrate-dependent Cell Migration, Cell Attachment To Substrate Cell Chemotaxis Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Chemotaxis Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Response To Virus Positive Regulation Of Immune Response To Tumor Cell Cell Adhesion Negative Regulation By Host Of Viral Transcription Inflammatory Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Negative Regulation Of Viral Transcription Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Calcium-mediated Signaling Response To External Stimulus Regulation Of Lymphocyte Migration Interaction With Symbiont Chemotaxis Substrate-dependent Cell Migration Positive Regulation Of Axon Extension Establishment Of Chromosome Localization Viral Entry Into Host Cell Regulation Of Calcium-mediated Signaling Entry Into Host Cell	Susceptibility To T Cell Mediated Cytotoxicity Apoptotic Process Positive Regulation Of Innate Immune Response Programmed Cell Death Cell Death Death Susceptibility To Natural Killer Cell Mediated Cytotoxicity Regulation Of Innate Immune Response Positive Regulation Of Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immune Response To Tumor Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Immune Response Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Immune System Process Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Adaptive Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Adaptive Immune Response Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Immune System Process Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell-cell Junction Organization Viral Entry Into Host Cell Entry Into Host Cell Positive Regulation Of Cell Activation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Cellular Component Assembly Coreceptor-mediated Virion Attachment To Host Cell Positive Regulation Of Sequestering Of Zinc Ion Regulation Of Defense Response To Virus Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of T Cell Mediated Cytotoxicity Adherens Junction Organization Regulation Of T Cell Mediated Cytotoxicity Immune Response-regulating Signaling Pathway Cellular Response To Tumor Necrosis Factor Regulation Of Cell Activation Signal Transduction Positive Regulation Of Leukocyte Mediated Cytotoxicity Interaction With Host
Tagcloud ?			2alpha 2beta abcb1b additive biexponential clearance designated dimeric erb3 fn14 fused gelonin hsgz humanized id immunotoxin inducer kills luc mcf7 mdr mdr1 pharmacokinetic synergistic t1 toxin translated tweak
Tagcloud (Difference) ?			2alpha 2beta abcb1b additive biexponential clearance designated dimeric erb3 fn14 fused gelonin hsgz humanized id immunotoxin inducer kills luc mcf7 mdr mdr1 pharmacokinetic synergistic t1 toxin translated tweak
Tagcloud (Intersection) ?