SLC30A2 and CD52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC30A2	CD52
Description		solute carrier family 30 member 2	CD52 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Lysosome Lysosomal Membrane Endosome Late Endosome Plasma Membrane Endosome Membrane Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Zymogen Granule Membrane Secretory Vesicle	Extracellular Region Plasma Membrane Membrane Sperm Midpiece Side Of Membrane
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Monoatomic Cation Transmembrane Transporter Activity Antiporter Activity Identical Protein Binding Metal Ion Binding Zinc:proton Antiporter Activity
	Biological Process	Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Response To Zinc Ion Transmembrane Transport Zinc Ion Import Into Organelle Zinc Ion Transmembrane Transport Zinc Export Across Plasma Membrane Zinc Ion Import Into Secretory Vesicle Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Lysosome Zinc Ion Import Into Mitochondrion	Positive Regulation Of Cytosolic Calcium Ion Concentration Respiratory Burst
Pathways		Zinc efflux and compartmentalization by the SLC30 family	Post-translational modification: synthesis of GPI-anchored proteins
Drugs			Alemtuzumab
Diseases
GWAS			Eosinophil count ( 32888494) Monocyte percentage of white cells ( 27863252)
Interacting Genes		67 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 ERGIC3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2	4 interacting genes: AQP6 CMTM2 LMNA SLC30A2
Entrez ID		7780	1043
HPRD ID		18057	00257
Ensembl ID		ENSG00000158014	ENSG00000169442
Uniprot IDs		Q9BRI3	P31358 V9HWN9
PDB IDs			6OBD
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Plasma Membrane Connexin Complex Gap Junction Channel Activity Gap Junction Renal Water Transport Gap Junction Assembly Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity CCR1 Chemokine Receptor Binding Amino Acid Import Across Plasma Membrane Amino Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transport Thyroid Hormone Transmembrane Transporter Activity Metal Ion Transport Protein Binding Positive Regulation Of Immune System Process Monoatomic Cation Transport Aromatic Amino Acid Transport	PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament Nuclear Pore Localization Zinc:proton Antiporter Activity Zinc Ion Import Into Lysosome Zinc Export Across Plasma Membrane Monoatomic Anion Channel Activity Renal Water Transport Negative Regulation Of Mesenchymal Cell Proliferation Vacuolar Transmembrane Transport Ammonium Transmembrane Transport Ammonium Channel Activity Ventricular Cardiac Muscle Cell Development Zinc Ion Import Into Organelle Secretory Vesicle Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Nuclear Lamina Water Channel Activity Protein Localization To Nuclear Envelope Carbon Dioxide Transport Zymogen Granule Membrane Monoatomic Cation Transmembrane Transporter Activity Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Nuclear Envelope Organization Zinc Ion Transmembrane Transporter Activity One-carbon Compound Transport Water Transport Nuclear Migration Zinc Ion Transport Zinc Ion Transmembrane Transport Inorganic Cation Transmembrane Transport Nucleus Localization Intracellular Zinc Ion Homeostasis Fluid Transport Regulation Of Mesenchymal Cell Proliferation Inorganic Ion Transmembrane Transport Channel Activity Nuclear Lumen Negative Regulation Of Muscle Hypertrophy
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