TMEM65 and IGSF9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM65	IGSF9
Description		transmembrane protein 65	immunoglobulin superfamily member 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Intercalated Disc Membrane	Plasma Membrane Membrane Axon Dendrite Synapse Inhibitory Synapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Cardiac Ventricle Development Cardiac Conduction Regulation Of Cardiac Conduction	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Nervous System Development Axon Guidance Dendrite Development Cell Differentiation Regulation Of Synapse Organization Dendrite Self-avoidance Regulation Of Synapse Maturation
Pathways
Drugs
Diseases
GWAS		Fear of minor pain ( 28701861)	Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		33 interacting genes: ABHD16A AQP6 ARL13B CYB561 CYBRD1 EBP ERGIC3 FAM174A FAM209A GJA8 GPR42 HSD17B11 IGSF9 IL3RA JAGN1 JPH1 LMNA MSMO1 PDZK1IP1 PTGES PVR REEP4 RETREG3 SCN3B SLC10A6 SLC18A1 SLC35H1 SLC7A8 TIMMDC1 TMEM101 TMEM80 TMX2 ZFYVE27	5 interacting genes: ASCC2 CYB5B PAQR5 SHANK3 TMEM65
Entrez ID		157378	57549
HPRD ID		14102	10001
Ensembl ID		ENSG00000164983	ENSG00000085552
Uniprot IDs		Q6PI78	Q9P2J2
PDB IDs			1V5J
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Ascorbate Homeostasis Transmembrane Monodehydroascorbate Reductase Activity Endoplasmic Reticulum Transmembrane Transport Protein Binding	Nitric-oxide Synthase Complex Nitrite Reductase (NO-forming) Activity Ribosome-associated Ubiquitin-dependent Protein Catabolic Process RQC-trigger Complex Guanylate Kinase-associated Protein Clustering Vocal Learning Negative Regulation Of Cell Volume Neuron Spine Postsynaptic Density Assembly Positive Regulation Of Long-term Neuronal Synaptic Plasticity AMPA Glutamate Receptor Clustering Synaptic Receptor Adaptor Activity Regulation Of Synapse Structural Plasticity Positive Regulation Of Synapse Structural Plasticity NMDA Glutamate Receptor Clustering Observational Learning Striatal Medium Spiny Neuron Differentiation Cardiac Ventricle Development DNA Alkylation Repair Positive Regulation Of Glutamate Receptor Signaling Pathway Postsynaptic Specialization Assembly GABAergic Neuron Differentiation Regulation Of Glutamate Receptor Signaling Pathway Neurotransmitter-gated Ion Channel Clustering DNA Repair Complex Auditory Behavior Regulation Of Long-term Synaptic Depression Mechanosensory Behavior Dendritic Spine Morphogenesis Postsynaptic Density Organization Nitric Oxide Biosynthetic Process Brain Morphogenesis Vocalization Behavior Positive Regulation Of Long-term Synaptic Potentiation K63-linked Polyubiquitin Modification-dependent Protein Binding Postsynaptic Specialization Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cardiac Conduction
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