SAA2 and LAMA1

Number of citations of the paper that reports this interaction (PMID 8995276)
1

Data Source:
HPRD (in vitro)

		SAA2	LAMA1
Gene Name		serum amyloid A2	laminin, alpha 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	High-density Lipoprotein Particle Extracellular Vesicular Exosome	Extracellular Region Proteinaceous Extracellular Matrix Basement Membrane Laminin-1 Complex Laminin-3 Complex Extracellular Space Cell-cell Junction Extracellular Matrix
	Molecular Function		Receptor Binding Extracellular Matrix Structural Constituent Protein Binding Glycosphingolipid Binding
	Biological Process	Acute-phase Response	Morphogenesis Of An Epithelial Sheet Cell Adhesion Cell Surface Receptor Signaling Pathway Axon Guidance Regulation Of Cell Adhesion Extracellular Matrix Organization Regulation Of Cell Migration Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Embryonic Development Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Retinal Blood Vessel Morphogenesis
Pathways			Axon guidance Laminin interactions ECM proteoglycans L1CAM interactions Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS			Response to citalopram treatment ( 22760553) Type 2 diabetes ( 22693455)
Protein-Protein Interactions		3 interactors: APOA1 COL4A1 LAMA1	19 interactors: ACHE APCS APP C3 COL7A1 DAG1 FBLN2 HSPG2 ITGA1 ITGA2 ITGB1 MEP1A NID1 NT5E PLAT PLG SAA1 SAA2 TMPRSS6
Entrez ID		6289	284217
HPRD ID		00098	01033
Ensembl ID		ENSG00000134339	ENSG00000101680
Uniprot IDs		P0DJI9	P25391
PDB IDs
Enriched GO Terms of Interacting Partners?		Retinal Blood Vessel Morphogenesis Retina Vasculature Morphogenesis In Camera-type Eye Retina Vasculature Development In Camera-type Eye Axon Development Chemotaxis Neuron Projection Development Neuron Development Regulation Of Embryonic Development Neuron Differentiation Cell Projection Organization Negative Regulation Of Cell Adhesion Molecule Production Retina Development In Camera-type Eye Locomotion Branching Morphogenesis Of An Epithelial Tube Negative Regulation Of Interleukin-1 Beta Secretion Movement Of Cell Or Subcellular Component Generation Of Neurons Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Neurogenesis Negative Regulation Of Interleukin-1 Secretion Cell Development Response To External Stimulus Establishment Of Epithelial Cell Apical/basal Polarity Receptor-mediated Endocytosis High-density Lipoprotein Particle Clearance Camera-type Eye Development Extracellular Matrix Organization Extracellular Structure Organization Epithelial Tube Morphogenesis Protein Oxidation Axon Guidance Eye Development Negative Regulation Of Heterotypic Cell-cell Adhesion Establishment Of Apical/basal Cell Polarity Negative Regulation Of Cytokine Secretion Involved In Immune Response High-density Lipoprotein Particle Assembly Polarized Epithelial Cell Differentiation Nervous System Development Blood Vessel Morphogenesis Tube Morphogenesis Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Cholesterol Esterification Regulation Of Intestinal Cholesterol Absorption Phospholipid Homeostasis Peptidyl-methionine Modification Establishment Of Monopolar Cell Polarity Gland Development	Extracellular Matrix Organization Extracellular Structure Organization Blood Coagulation Hemostasis Response To Wounding Cell-matrix Adhesion Regulation Of Body Fluid Levels Negative Regulation Of Wound Healing Wound Healing Cell-substrate Adhesion Extracellular Matrix Disassembly Cell Adhesion Fibrinolysis Regulation Of Inflammatory Response Locomotion Regulation Of Wound Healing Acute-phase Response Viral Entry Into Host Cell Chemotaxis Entry Into Host Cell Regulation Of Cell Adhesion Positive Regulation Of Cell Adhesion Movement Of Cell Or Subcellular Component Axon Guidance Negative Regulation Of Blood Coagulation Response To Stress Regulation Of Cell-substrate Adhesion Negative Regulation Of Coagulation Acute Inflammatory Response Leukocyte Migration Cell Migration Axonogenesis Cell Motility Cell Adhesion Mediated By Integrin Basement Membrane Organization Axon Development Positive Regulation Of Endocytosis Regulation Of Blood Coagulation Cell Morphogenesis Involved In Neuron Differentiation Interaction With Host Negative Regulation Of Inflammatory Response Positive Regulation Of Cell-substrate Adhesion Integrin-mediated Signaling Pathway Neuron Projection Morphogenesis Regulation Of Protein Metabolic Process Formation Of Primary Germ Layer Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Cell Morphogenesis Involved In Differentiation Positive Regulation Of Transport
Tagcloud ?		10scn 1rn alleles amyloidosis c57bl chemotaxis del deposit differently efficacious encoded equally familiar fever formyl fpr2 isoforms mediterranean mobilization modulating predominant preference robust saa1 selectivity tlr2 tlr4lps toll	annexin2 col1a1 committed desensitized ecm fbln1 fbn2 fibrillin fibullin fn1 has1 hsc hyaluronan ifi ifi44l ifit1 ifnbeta isgf3 laminin mineralization modifies niche opn osteoblast osteoblasts osteoimmunology osteopontin pinpoints timing
Tagcloud (Difference) ?		10scn 1rn alleles amyloidosis c57bl chemotaxis del deposit differently efficacious encoded equally familiar fever formyl fpr2 isoforms mediterranean mobilization modulating predominant preference robust saa1 selectivity tlr2 tlr4lps toll	annexin2 col1a1 committed desensitized ecm fbln1 fbn2 fibrillin fibullin fn1 has1 hsc hyaluronan ifi ifi44l ifit1 ifnbeta isgf3 laminin mineralization modifies niche opn osteoblast osteoblasts osteoimmunology osteopontin pinpoints timing
Tagcloud (Intersection) ?