SAA2 and LAMA1

Number of citations of the paper that reports this interaction (PubMedID 8995276)
0

Data Source:
HPRD (in vitro)

		SAA2	LAMA1
Description		serum amyloid A2	laminin subunit alpha 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region High-density Lipoprotein Particle Extracellular Exosome	Extracellular Region Basement Membrane Laminin-1 Complex Laminin-3 Complex Extracellular Space Cell-cell Junction Membrane Extracellular Matrix Laminin Complex Protein Complex Involved In Cell-matrix Adhesion
	Molecular Function	Protein Binding	Signaling Receptor Binding Extracellular Matrix Structural Constituent Protein Binding Glycosphingolipid Binding
	Biological Process	Acute-phase Response	Morphogenesis Of An Epithelial Sheet Cell Adhesion Cell Surface Receptor Signaling Pathway Tissue Development Regulation Of Cell Adhesion Regulation Of Cell Migration Neuron Projection Development Establishment Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cell Adhesion Regulation Of Embryonic Development Positive Regulation Of Muscle Cell Differentiation Retina Development In Camera-type Eye Epithelial Tube Branching Involved In Lung Morphogenesis Branching Involved In Salivary Gland Morphogenesis Retinal Blood Vessel Morphogenesis Regulation Of Basement Membrane Organization Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways			Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans L1CAM interactions MET activates PTK2 signaling Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Drugs			Lanoteplase
Diseases
GWAS			Adverse response to drug ( 30420678) Response to citalopram treatment ( 22760553) Type 2 diabetes ( 22693455 30054458 30297969 32499647)
Interacting Genes		4 interacting genes: CIDEB COL4A1 LAMA1 TEAD2	23 interacting genes: ACHE APCS APP C3 COL18A1 COL7A1 DAG1 FBLN2 HSPG2 ITGA1 ITGA2 ITGB1 MEP1A NID1 NT5E PLAT PLG SAA1 SAA2 TGM2 TMPRSS6 UBC USP7
Entrez ID		6289	284217
HPRD ID		00098	01033
Ensembl ID		ENSG00000134339	ENSG00000101680
Uniprot IDs		P0DJI9	P25391
PDB IDs
Enriched GO Terms of Interacting Partners?		Retinal Blood Vessel Morphogenesis Retina Vasculature Morphogenesis In Camera-type Eye Morphogenesis Of An Epithelium Tube Morphogenesis Tissue Morphogenesis Basement Membrane Epithelial Tube Morphogenesis Blood Vessel Morphogenesis Extracellular Matrix Structural Constituent Branching Morphogenesis Of An Epithelial Tube Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure TEAD-YAP Complex Laminin-1 Complex Laminin-3 Complex Lateral Mesoderm Development Laminin Complex Lipid Droplet Fusion Collagen Type IV Trimer Glycosphingolipid Binding Paraxial Mesoderm Development Regulation Of Basement Membrane Organization Protein Complex Involved In Cell-matrix Adhesion Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Anatomical Structure Morphogenesis Platelet-derived Growth Factor Binding Notochord Development Very-low-density Lipoprotein Particle Assembly Branching Involved In Salivary Gland Morphogenesis Lipid Transfer Activity Positive Regulation Of Integrin-mediated Signaling Pathway Epithelial Cell Differentiation COPI-coated Vesicle Collagen-activated Signaling Pathway Extracellular Matrix Signal Transduction Renal Tubule Morphogenesis COPII Vesicle Coat Establishment Of Epithelial Cell Apical/basal Polarity COPII-coated Vesicle Cargo Loading Morphogenesis Of An Epithelial Sheet Phosphatidic Acid Binding Plasma Lipoprotein Particle Assembly Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Epithelial Tube Branching Involved In Lung Morphogenesis Regulation Of Integrin-mediated Signaling Pathway Polarized Epithelial Cell Differentiation Execution Phase Of Apoptosis	Extracellular Exosome Laminin Binding Basement Membrane Extracellular Matrix Extracellular Region Cell Surface Extracellular Space Extracellular Matrix Organization Extracellular Structure Organization Collagen Binding Involved In Cell-matrix Adhesion Cell Adhesion External Side Of Plasma Membrane Cell-matrix Adhesion Collagen Binding Cell-substrate Adhesion Integrin Alpha1-beta1 Complex High-density Lipoprotein Particle Integrin Alpha2-beta1 Complex Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Regulation Of Cell Adhesion Integrin Complex Response To Muscle Activity Calcium Ion Binding Trans-synaptic Signaling By BDNF Basement Membrane Organization Focal Adhesion Acute-phase Response Peptidase Activity Positive Regulation Of Multicellular Organismal Process Regulation Of Spontaneous Synaptic Transmission Regulation Of Wound Healing Modulation Of Chemical Synaptic Transmission Endoplasmic Reticulum Lumen Laminin-1 Binding Positive Regulation Of Cell Adhesion Integrin Binding Serine-type Endopeptidase Activity Inflammatory Response Regulation Of Apoptotic Cell Clearance Regulation Of Response To Wounding Acute Inflammatory Response Positive Regulation Of Wound Healing Proteolysis Branching Involved In Salivary Gland Morphogenesis Negative Regulation Of Fibrinolysis Trans-synaptic Signaling, Modulating Synaptic Transmission Negative Regulation Of Wound Healing Cell Migration Regulation Of Multicellular Organismal Process Regulation Of Cell Communication
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