S100A4 and MYH2

Number of citations of the paper that reports this interaction (PubMedID 12756252)
0

Data Source:
HPRD (in vivo, in vitro)

		S100A4	MYH2
Description		S100 calcium binding protein A4	myosin heavy chain 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Matrix Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Cytosol Muscle Myosin Complex Cell-cell Junction Myosin Complex Myosin II Complex Myofibril Sarcomere Myosin Filament Protein-containing Complex Supramolecular Fiber
	Molecular Function	RNA Binding Actin Binding Calcium Ion Binding Protein Binding Chemoattractant Activity Identical Protein Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Actin Filament Binding
	Biological Process	Epithelial To Mesenchymal Transition Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Chemotaxis	Muscle Contraction Muscle Filament Sliding
Pathways			Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis
Drugs		Trifluoperazine Copper
Diseases
GWAS		Pulse pressure ( 30578418)
Interacting Genes		29 interacting genes: ACTA1 ANXA2 BAG6 CCN3 CEP20 EGFR FCGR3A HSPB1 IFNB1 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 PPFIBP1 RHOU S100A1 S100B S100P SEPTIN2 SEPTIN6 SEPTIN7 SMAD3 SRPK2 TP53 TPM2 TPM3 UNC119	7 interacting genes: AMPD1 DGKD DUX4L9 OBSCN PRKCE PTK2B S100A4
Entrez ID		6275	4620
HPRD ID		15914	01173
Ensembl ID		ENSG00000196154	ENSG00000125414
Uniprot IDs		P26447	Q9UKX2
PDB IDs		1M31 2LNK 2MRD 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4CFQ 4CFR 4ETO 4HSZ 5LPU 6T58 7PSP 7PSQ
Enriched GO Terms of Interacting Partners?		Cytoplasm Identical Protein Binding Cleavage Furrow Actin Filament Binding Myosin II Complex Myosin Filament Spindle Sperm Annulus Stress Fiber Microfilament Motor Activity Cytoskeleton-dependent Cytokinesis Supramolecular Fiber Cytosol S100 Protein Binding Cell Division Site Septin Ring Septin Complex Cytoskeletal Motor Activity Myosin Complex Regulation Of Developmental Process Actin Filament-based Movement Regulation Of Cell Shape Cellular Response To Actinomycin D Myosin II Filament Calcium-dependent Protein Binding Cadherin Binding Cytoskeleton Supramolecular Fiber Organization Midbody Response To Actinomycin D Muscle Thin Filament Tropomyosin Muscle Contraction Regulation Of Protein Kinase C Signaling Cellular Response To UV-C Actin Binding ADP Binding Actin-mediated Cell Contraction Negative Regulation Of Protein Catabolic Process Regulation Of Cell Morphogenesis Regulation Of Plasma Membrane Repair Muscle System Process Nucleotide Binding Cell Adhesion Cellular Developmental Process System Process Actin Cytoskeleton Regulation Of Protein Localization Sarcomere Positive Regulation Of Gene Expression Regulation Of Protein Processing	Signaling Receptor Activator Activity Kinase Activity AMP Deaminase Activity Phosphate-containing Compound Metabolic Process ATP Binding Positive Regulation Of Protein Polymerization Regulation Of Actin Filament Polymerization Neurotransmitter Receptor Regulator Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of B Cell Chemotaxis Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Actin Filament Polymerization Negative Regulation Of Monoatomic Ion Transport Phosphorylation Protein Kinase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell-substrate Adhesion TRAM-dependent Toll-like Receptor 4 Signaling Pathway Ethanol Binding Negative Regulation Of Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Clathrin-dependent Endocytosis Protein Localization To M-band Regulation Of Actin Polymerization Or Depolymerization Regulation Of Calcium Ion Transmembrane Transport Cell Activation Involved In Immune Response Regulation Of Actin Filament Length Leukocyte Activation Involved In Immune Response Positive Regulation Of Synaptic Transmission Cell Activation Activation Of Janus Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Toxin Catabolic Process IMP Salvage GMP Salvage Perinuclear Region Of Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Signal Transduction Positive Regulation Of Mucus Secretion Positive Regulation Of Cytoskeleton Organization Diacylglycerol Catabolic Process Deaminase Activity NMDA Selective Glutamate Receptor Complex Transferase Activity Signal Complex Assembly Positive Regulation Of Cell Communication Regulation Of Signal Transduction Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Signaling Regulation Of Cell-substrate Adhesion Regulation Of Calcium Ion Transport
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