RPS14 and RLIM

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPS14	RLIM
Gene Name		ribosomal protein S14	ring finger protein, LIM domain interacting
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Mitochondrion Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Transcriptional Repressor Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding Translation Regulator Activity MRNA 5'-UTR Binding	Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Ribosomal Small Subunit Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination Regulation Of Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Erythrocyte Differentiation Maturation Of SSU-rRNA Cellular Protein Metabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Random Inactivation Of X Chromosome
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		8 interactors: APP CALM1 PEX6 RBBP6 RLIM SMAD2 TAF9 TMEM33	27 interactors: ESR1 ISL1 LDB1 LDB2 LHX1 LHX2 LHX3 LIMK1 LMO2 LNX2 PDLIM1 REXO1 RPS14 SIN3A SMURF2 SNX17 SS18L1 STAT6 STMN1 TERF1 TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2
Entrez ID		6208	51132
HPRD ID		00562	02304
Ensembl ID		ENSG00000164587	ENSG00000131263
Uniprot IDs		P62263	Q9NVW2
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Platelet Degranulation Random Inactivation Of X Chromosome Protein Stabilization Growth Secretion By Cell Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Synaptic Growth At Neuromuscular Junction Regulation Of Protein Stability Secretion Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Protein Import Into Peroxisome Matrix, Translocation Collateral Sprouting In Absence Of Injury Zygotic Specification Of Dorsal/ventral Axis Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Transcription Initiation From RNA Polymerase II Promoter Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of High Voltage-gated Calcium Channel Activity Cellular Protein Modification Process Platelet Activation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Primary MiRNA Processing Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Gene Expression, Epigenetic Regulation Of Nodal Signaling Pathway Axon Choice Point Recognition Common-partner SMAD Protein Phosphorylation DNA-templated Transcription, Initiation Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Protein Metabolic Process Establishment Of Localization In Cell Neuron Remodeling Regulation Of Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Developmental Growth Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Transcription From RNA Polymerase II Promoter Detection Of Calcium Ion SMAD Protein Complex Assembly Regulation Of Cell Communication By Electrical Coupling Dosage Compensation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Phosphoprotein Phosphatase Activity	Protein K48-linked Ubiquitination Protein Polyubiquitination Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Activation Of Innate Immune Response Negative Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Innate Immune Response RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Protein K11-linked Ubiquitination Negative Regulation Of RNA Biosynthetic Process Cellular Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Stimulus Positive Regulation Of Immune Response Gene Expression Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Regulation Of Immune System Process Regulation Of Innate Immune Response System Development Mitotic Spindle Assembly Checkpoint
Tagcloud ?		aquaticus eubacteria identities intergenic l14 l15 l18 l24 l30 l5 l6 maritima mesophile operon operons overlapped rpl14 rpl15 rps17 rps8 s10 s17 spacer spc thermophile thermophilus thermotoga thermus	activators acts clim coactivator deacetylase embryonic encoded enlarge exerts hdac homeodomain inactivation inducer interacts interfering p53 physically playing prevents recruiting repressed repression repressor s1 s4 sin3a sp1 tried
Tagcloud (Difference) ?		aquaticus eubacteria identities intergenic l14 l15 l18 l24 l30 l5 l6 maritima mesophile operon operons overlapped rpl14 rpl15 rps17 rps8 s10 s17 spacer spc thermophile thermophilus thermotoga thermus	activators acts clim coactivator deacetylase embryonic encoded enlarge exerts hdac homeodomain inactivation inducer interacts interfering p53 physically playing prevents recruiting repressed repression repressor s1 s4 sin3a sp1 tried
Tagcloud (Intersection) ?