RPL41 and SDCBP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RPL41	SDCBP2
Description		ribosomal protein L41	syndecan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Ribosome Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Structural Constituent Of Ribosome Protein Binding MRNA 5'-UTR Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Cytoplasmic Translation Translation	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic sclerosis ( 21779181)	Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		9 interacting genes: APP CSNK2B DAPK1 IKBKG MAPK14 NUPR1 PRNP SDCBP2 SRPK2	66 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PDCD6IP PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		6171	27111
HPRD ID		17999	18032
Ensembl ID		ENSG00000229117	ENSG00000125775
Uniprot IDs		A0A024RB15 P62945	Q9H190
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5LKS 5OA3 5VYC 6G5H 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMW 6ZOJ 6ZOK 6ZON 6ZP4 6ZVJ 7A09 7F5S 7K5I 7QP6 7QP7 7QVP 7R4X 7TQL 7XNX 7XNY 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 9BKD 9BLN 9C3H 9G8M 9G8O
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neuron Apoptotic Process Intracellular Signal Transduction Protein-containing Complex Assembly Protein-containing Complex Organization Regulation Of Proteolysis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Signal Transduction Regulation Of Neuron Apoptotic Process Regulation Of Response To Endoplasmic Reticulum Stress Defense Response Negative Regulation Of Long-term Synaptic Potentiation Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Regulation Of Apoptotic Process Cellular Component Assembly Intracellular Copper Ion Homeostasis Regulation Of Programmed Cell Death Regulation Of Protein Metabolic Process Protein Serine/threonine Kinase Activity Apoptotic Process Copper Ion Homeostasis Programmed Cell Death Cell Death Regulation Of Cell Population Proliferation Cellular Response To Copper Ion Molecular Function Activator Activity Identical Protein Binding Regulation Of Cell Cycle Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Catabolic Process Response To Copper Ion Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Intracellular Signal Transduction Response To Stress Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Cell Population Proliferation Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Primary Metabolic Process Regulation Of Glycolytic Process Cellular Response To Amyloid-beta Regulation Of Cell Communication Cytoplasm Regulation Of Signaling Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of Calcium-mediated Signaling	Protein Binding
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