RPL37A and IFNGR2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPL37A	IFNGR2
Gene Name		ribosomal protein L37a	interferon gamma receptor 2 (interferon gamma transducer 1)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Constituent Of Ribosome Poly(A) RNA Binding Metal Ion Binding	Cytokine Receptor Activity Interferon-gamma Receptor Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Cell Surface Receptor Signaling Pathway Response To Virus Cytokine-mediated Signaling Pathway Interferon-gamma-mediated Signaling Pathway Regulation Of Interferon-gamma-mediated Signaling Pathway
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Regulation of IFNG signaling
Drugs			Interferon gamma-1b
Diseases
GWAS			Crohn's disease ( 22936669 23128233) Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: APP BUB3 CTPS2 IFNGR2 LRIF1 MAGEA6 NKX3-1	8 interactors: ANXA5 CAMK2D DNAJA3 IFNG IFNGR1 JAK2 NR3C1 RPL37A
Entrez ID		6168	3460
HPRD ID		17997	00956
Ensembl ID			ENSG00000159128
Uniprot IDs		P61513	A8K881 E7EUY1 P38484
PDB IDs		3J3B
Enriched GO Terms of Interacting Partners?		Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction 'de Novo' CTP Biosynthetic Process Positive Regulation Of Androgen Secretion Regulation Of Proteolysis Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Collateral Sprouting In Absence Of Injury Negative Regulation Of Estrogen Receptor Binding Collateral Sprouting Axon Midline Choice Point Recognition Intracellular Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Axon Choice Point Recognition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Receptor Binding Regulation Of Cell Division Regulation Of Binding Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Neuron Remodeling Positive Regulation Of Cell Cycle Dorsal Aorta Development Positive Regulation Of Proteolysis Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Attachment Of Spindle Microtubules To Kinetochore	Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Response To Interferon-gamma Regulation Of Cytokine-mediated Signaling Pathway Interferon-gamma-mediated Signaling Pathway Cellular Response To Interferon-gamma Regulation Of Innate Immune Response Response To Organic Substance Response To Cytokine Innate Immune Response Cytokine-mediated Signaling Pathway Regulation Of Heart Contraction Cellular Response To Cytokine Stimulus Immune Response Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Defense Response Positive Regulation Of Cell Death Positive Regulation Of Interleukin-1 Beta Production Regulation Of Apoptotic Process Positive Regulation Of Phosphatase Activity Regulation Of The Force Of Heart Contraction Positive Regulation Of Interleukin-1 Production Regulation Of Cell Death Homeostasis Of Number Of Cells Regulation Of Signal Transduction Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Cell Proliferation Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Proteolysis Positive Regulation Of Cell Activation Regulation Of Signaling Regulation Of Immune Response Positive Regulation Of Dephosphorylation Regulation Of Interleukin-1 Beta Production Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Tumor Necrosis Factor Production Establishment Of Protein Localization To Organelle Signal Transduction Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of JAK-STAT Cascade Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Stress Regulation Of Steroid Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Signaling
Tagcloud ?		3d actb algorithms aspirates calculating cancellous cd71 cube cultivated cultivation genorm hprt1 hypoxanthine mscs normfinder osteogenic phosphoribosyltransferase porous prerequisite qrt rgs scaffolds stably taqman tata tbp te tfrc	allelic candidiasis cybb definition designation errors il12b il12rb1 immunological impair inborn intramacrophagic irf8 isg15 mendelian msmd mycobacteria nemo overt parasites penetrance perhaps physiologically predisposition recapitulate salmonellosis virulent weakly
Tagcloud (Difference) ?		3d actb algorithms aspirates calculating cancellous cd71 cube cultivated cultivation genorm hprt1 hypoxanthine mscs normfinder osteogenic phosphoribosyltransferase porous prerequisite qrt rgs scaffolds stably taqman tata tbp te tfrc	allelic candidiasis cybb definition designation errors il12b il12rb1 immunological impair inborn intramacrophagic irf8 isg15 mendelian msmd mycobacteria nemo overt parasites penetrance perhaps physiologically predisposition recapitulate salmonellosis virulent weakly
Tagcloud (Intersection) ?